| Literature DB >> 31646273 |
Angelo Avogaro1, Saula Vigili De Kreutzenberg1, Gian Paolo Fadini1.
Abstract
Patients with type 2 diabetes mellitus die most frequently from cardiovascular disease. Metabolic control is mandatory both for preventing long-term complications and for reducing the negative effects of the exposure of the other risk factors. In this article, we will describe the most commonly used glucose-lowering agents, the pathophysiological mechanisms underlying their cardiovascular protection, the available evidence-based data for this protection, and the contraindications and potential adverse effects.Entities:
Keywords: cardiovascular outcome trials; diabetes type 2; glucagon-like peptide 1 receptor agonists; macrovascular complications; microvascular complications; sodium–glucose cotransporters 2
Year: 2018 PMID: 31646273 PMCID: PMC6739886 DOI: 10.1097/XCE.0000000000000139
Source DB: PubMed Journal: Cardiovasc Endocrinol Metab ISSN: 2574-0954