Literature DB >> 31646271

Pathophysiology of cardiovascular disease in diabetes mellitus.

Gerardo Rodriguez-Araujo1,2, Hironori Nakagami3.   

Abstract

Diabetes mellitus elicits cellular, epigenetic, and post-translational changes that directly or indirectly affect the biology of the vasculature and other metabolic systems resulting in the apparition of cardiovascular disease. In this review, we provide a current perspective on the most recent discoveries in this field, with particular focus on hyperglycemia- induced pathology in the cardiovascular system. We also provide perspective on the clinical importance of molecular targeting of cardiovascular and diabetes mellitus therapies to treat hyperglycemia, inflammation, thrombosis, dyslipidemia, atherosclerosis, and hypertension.
Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

Entities:  

Keywords:  atherosclerosis; cardiovascular disease; cell signaling; cholesterol toxicity; diabetes mellitus; dyslipidemia; epigenetics; glucose toxicity; inflammation; pathophysiology

Year:  2018        PMID： 31646271      PMCID： PMC6739883          DOI： 10.1097/XCE.0000000000000141

Source DB:  PubMed          Journal:  Cardiovasc Endocrinol Metab        ISSN： 2574-0954


  70 in total

1.  Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells.

Authors:  Luciano Pirola; Aneta Balcerczyk; Richard W Tothill; Izhak Haviv; Antony Kaspi; Sebastian Lunke; Mark Ziemann; Tom Karagiannis; Stephen Tonna; Adam Kowalczyk; Bryan Beresford-Smith; Geoff Macintyre; Ma Kelong; Zhang Hongyu; Jingde Zhu; Assam El-Osta
Journal:  Genome Res       Date:  2011-09-02       Impact factor: 9.043

2.  Microvascular thrombosis, fibrinolysis, ischemic injury, and death after cerebral thromboembolism are affected by levels of circulating α2-antiplasmin.

Authors:  Guy L Reed; Aiilyan K Houng; Dong Wang
Journal:  Arterioscler Thromb Vasc Biol       Date:  2014-09-25       Impact factor: 8.311

3.  Plasma MicroRNA-126-5p is Associated with the Complexity and Severity of Coronary Artery Disease in Patients with Stable Angina Pectoris.

Authors:  Hai-Yu Li; Xin Zhao; Yu-Zhou Liu; Zhe Meng; Dan Wang; Fan Yang; Qiang-Wei Shi
Journal:  Cell Physiol Biochem       Date:  2016-08-09

Review 4.  Immunometabolic Regulation of Vascular Redox State: The Role of Adipose Tissue.

Authors:  Evangelos K Oikonomou; Charalambos Antoniades
Journal:  Antioxid Redox Signal       Date:  2017-08-28       Impact factor: 8.401

5.  MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor.

Authors:  Sufang Li; Jingyi Ren; Ning Xu; Jing Zhang; Qiang Geng; Chengfu Cao; Chongyou Lee; Junxian Song; Jingjin Li; Hong Chen
Journal:  J Mol Cell Cardiol       Date:  2014-07-03       Impact factor: 5.000

6.  Microemboli and microvascular obstruction in acute coronary thrombosis and sudden coronary death: relation to epicardial plaque histopathology.

Authors:  Robert S Schwartz; Allen Burke; Andrew Farb; David Kaye; John R Lesser; Timothy D Henry; Renu Virmani
Journal:  J Am Coll Cardiol       Date:  2009-12-01       Impact factor: 24.094

Review 7.  Metalloproteinases and vulnerable atherosclerotic plaques.

Authors:  Andrew C Newby
Journal:  Trends Cardiovasc Med       Date:  2007-11       Impact factor: 6.677

8.  A fully human, allosteric monoclonal antibody that activates the insulin receptor and improves glycemic control.

Authors:  Vinay Bhaskar; Ira D Goldfine; Daniel H Bedinger; Angela Lau; Hua F Kuan; Lisa M Gross; Masahisa Handa; Betty A Maddux; Susan R Watson; Shirley Zhu; Ajay J Narasimha; Raphael Levy; Lynn Webster; Sujeewa D Wijesuriya; Naichi Liu; Xiaorong Wu; David Chemla-Vogel; Catarina Tran; Steve R Lee; Steve Wong; Diane Wilcock; Mark L White; John A Corbin
Journal:  Diabetes       Date:  2012-03-08       Impact factor: 9.461

9.  Impact of diabetes on cardiovascular disease: an update.

Authors:  Alessandra Saldanha de Mattos Matheus; Lucianne Righeti Monteiro Tannus; Roberta Arnoldi Cobas; Catia C Sousa Palma; Carlos Antonio Negrato; Marilia de Brito Gomes
Journal:  Int J Hypertens       Date:  2013-03-04       Impact factor: 2.420

10.  Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4.

Authors:  J Xiao; Y Pan; X H Li; X Y Yang; Y L Feng; H H Tan; L Jiang; J Feng; X Y Yu
Journal:  Cell Death Dis       Date:  2016-06-23       Impact factor: 8.469
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  12 in total

1.  The Effects of Soy Products on Cardiovascular Risk Factors in Patients with Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials.

Authors:  Omid Asbaghi; Damoon Ashtary-Larky; Aya Mousa; Mahnaz Rezaei Kelishadi; Seyedeh Parisa Moosavian
Journal:  Adv Nutr       Date:  2021-09-30       Impact factor: 8.701

2.  Improved Endothelium-Dependent Relaxation of Thoracic Aorta in Niclosamide-Treated Diabetic Rats.

Authors:  Seckin Engin; Yesim Kaya Yasar; Elif Nur Barut; Sena F Sezen
Journal:  Cardiovasc Toxicol       Date:  2021-03-27       Impact factor: 3.231

3.  Sexual dimorphism in testosterone programming of cardiomyocyte development in sheep.

Authors:  Adel Ghnenis; Vasantha Padmanabhan; Arpita Vyas
Journal:  Am J Physiol Heart Circ Physiol       Date:  2022-02-04       Impact factor: 4.733

Review 4.  Dysregulation of 2-oxoglutarate-dependent dioxygenases by hyperglycaemia: does this link diabetes and vascular disease?

Authors:  Hannah L H Green; Alison C Brewer
Journal:  Clin Epigenetics       Date:  2020-04-28       Impact factor: 6.551

5.  Glucose Tolerance-Improving Activity of Helichrysoside in Mice and Its Structural Requirements for Promoting Glucose and Lipid Metabolism.

Authors:  Toshio Morikawa; Akifumi Nagatomo; Takahiro Oka; Yoshinobu Miki; Norihisa Taira; Megumi Shibano-Kitahara; Yuichiro Hori; Osamu Muraoka; Kiyofumi Ninomiya
Journal:  Int J Mol Sci       Date:  2019-12-14       Impact factor: 5.923

6.  Diet-induced prediabetes: effects of exercise treatment on risk factors for cardiovascular complications.

Authors:  Mluleki Luvuno; Andile Khathi; Musa V Mabandla
Journal:  Nutr Metab (Lond)       Date:  2021-04-22       Impact factor: 4.169

Review 7.  Therapeutic Effects and Safe Uses of Plant-Derived Polyphenolic Compounds in Cardiovascular Diseases: A Review.

Authors:  Badriyah Shadid Alotaibi; Munazza Ijaz; Manal Buabeid; Zelal Jaber Kharaba; Hafiza Sidra Yaseen; Ghulam Murtaza
Journal:  Drug Des Devel Ther       Date:  2021-11-20       Impact factor: 4.162

8.  Using Network Pharmacology to Explore the Mechanism of Panax notoginseng in the Treatment of Myocardial Fibrosis.

Authors:  Jingxue Han; Jingyi Hou; Yu Liu; Peng Liu; Tingting Zhao; Xinwei Wang
Journal:  J Diabetes Res       Date:  2022-03-25       Impact factor: 4.011

9.  Carotid intraplaque neovascularisation as a predictive factor for future vascular events in patients with mild and moderate carotid stenosis: an observational prospective study.

Authors:  Liuping Cui; Yingqi Xing; Yangyang Zhou; Lijuan Wang; Kangding Liu; Daofu Zhang; Ying Chen
Journal:  Ther Adv Neurol Disord       Date:  2021-06-19       Impact factor: 6.570

10.  Geranylgeranyl Transferase-I Knockout Inhibits Oxidative Injury of Vascular Smooth Muscle Cells and Attenuates Diabetes-Accelerated Atherosclerosis.

Authors:  Guo-Ping Chen; Jian Yang; Guo-Feng Qian; Wei-Wei Xu; Xiao-Qin Zhang
Journal:  J Diabetes Res       Date:  2020-08-10       Impact factor: 4.011
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