Literature DB >> 31643041

Effect of Simvastatin on Permeability in Cerebral Cavernous Malformation Type 1 Patients: Results from a Pilot Small Randomized Controlled Clinical Trial.

Marc C Mabray1, Arvind Caprihan2, Jeffrey Nelson3, Charles E McCulloch4, Atif Zafar5, Helen Kim3,4, Blaine L Hart6, Leslie Morrison5.   

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Year:  2019        PMID： 31643041      PMCID： PMC7176512          DOI： 10.1007/s12975-019-00737-4

Source DB:  PubMed          Journal:  Transl Stroke Res        ISSN： 1868-4483            Impact factor:   6.829


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  13 in total

1.  Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.

Authors:  Robert Shenkar; Amy Peiper; Heidy Pardo; Thomas Moore; Rhonda Lightle; Romuald Girard; Nicholas Hobson; Sean P Polster; Janne Koskimäki; Dongdong Zhang; Seán B Lyne; Ying Cao; Kiranj Chaudagar; Laleh Saadat; Carol Gallione; Peter Pytel; James K Liao; Douglas Marchuk; Issam A Awad
Journal:  Stroke       Date:  2019-03       Impact factor: 7.914

2.  Vascular permeability and iron deposition biomarkers in longitudinal follow-up of cerebral cavernous malformations.

Authors:  Romuald Girard; Maged D Fam; Hussein A Zeineddine; Huan Tan; Abdul Ghani Mikati; Changbin Shi; Michael Jesselson; Robert Shenkar; Meijing Wu; Ying Cao; Nicholas Hobson; Henrik B W Larsson; Gregory A Christoforidis; Issam A Awad
Journal:  J Neurosurg       Date:  2016-08-05       Impact factor: 5.115

3.  RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.

Authors:  Robert Shenkar; Changbin Shi; Cecilia Austin; Thomas Moore; Rhonda Lightle; Ying Cao; Lingjiao Zhang; Meijing Wu; Hussein A Zeineddine; Romuald Girard; David A McDonald; Autumn Rorrer; Carol Gallione; Peter Pytel; James K Liao; Douglas A Marchuk; Issam A Awad
Journal:  Stroke       Date:  2016-11-22       Impact factor: 7.914

4.  Atorvastatin Treatment of Cavernous Angiomas with Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial.

Authors:  Sean P Polster; Agnieszka Stadnik; Amy L Akers; Ying Cao; Gregory A Christoforidis; Maged D Fam; Kelly D Flemming; Romuald Girard; Nicholas Hobson; James I Koenig; Janne Koskimäki; Karen Lane; James K Liao; Cornelia Lee; Seán B Lyne; Nichol McBee; Leslie Morrison; Kristina Piedad; Robert Shenkar; Matthew Sorrentino; Richard E Thompson; Kevin J Whitehead; Hussein A Zeineddine; Daniel F Hanley; Issam A Awad
Journal:  Neurosurgery       Date:  2019-12-01       Impact factor: 4.654

5.  Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype.

Authors:  Asya L Borikova; Christopher F Dibble; Noah Sciaky; Christopher M Welch; Amy N Abell; Sompop Bencharit; Gary L Johnson
Journal:  J Biol Chem       Date:  2010-02-24       Impact factor: 5.157

6.  Vascular permeability in cerebral cavernous malformations.

Authors:  Abdul G Mikati; Omaditya Khanna; Lingjiao Zhang; Romuald Girard; Robert Shenkar; Xiaodong Guo; Akash Shah; Henrik B W Larsson; Huan Tan; Luying Li; Matthew S Wishnoff; Changbin Shi; Gregory A Christoforidis; Issam A Awad
Journal:  J Cereb Blood Flow Metab       Date:  2015-05-13       Impact factor: 6.200

Review 7.  Familial Cerebral Cavernous Malformations.

Authors:  Atif Zafar; Syed A Quadri; Mudassir Farooqui; Asad Ikram; Myranda Robinson; Blaine L Hart; Marc C Mabray; Catherine Vigil; Alan T Tang; Mark L Kahn; Howard Yonas; Michael T Lawton; Helen Kim; Leslie Morrison
Journal:  Stroke       Date:  2019-05       Impact factor: 7.914

8.  Dynamic contrast-enhanced MRI evaluation of cerebral cavernous malformations.

Authors:  Blaine L Hart; Saeid Taheri; Gary A Rosenberg; Leslie A Morrison
Journal:  Transl Stroke Res       Date:  2013-09-21       Impact factor: 6.829

9.  Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity.

Authors:  Rebecca A Stockton; Robert Shenkar; Issam A Awad; Mark H Ginsberg
Journal:  J Exp Med       Date:  2010-03-22       Impact factor: 14.307

Review 10.  Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel.

Authors:  Amy Akers; Rustam Al-Shahi Salman; Issam A Awad; Kristen Dahlem; Kelly Flemming; Blaine Hart; Helen Kim; Ignacio Jusue-Torres; Douglas Kondziolka; Cornelia Lee; Leslie Morrison; Daniele Rigamonti; Tania Rebeiz; Elisabeth Tournier-Lasserve; Darrel Waggoner; Kevin Whitehead
Journal:  Neurosurgery       Date:  2017-05-01       Impact factor: 4.654
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  3 in total

1.  Transcriptome Analysis Reveals Altered Expression of Genes Involved in Hypoxia, Inflammation and Immune Regulation in Pdcd10-Depleted Mouse Endothelial Cells.

Authors:  Carmela Fusco; Grazia Nardella; Lucio Di Filippo; Elisabetta Dejana; Davide Cacchiarelli; Antonio Petracca; Lucia Micale; Matteo Malinverno; Marco Castori
Journal:  Genes (Basel)       Date:  2022-05-27       Impact factor: 4.141

Review 2.  Tailored Treatment Options for Cerebral Cavernous Malformations.

Authors:  Jessa E Hoffman; Blake Wittenberg; Brent Morel; Zach Folzenlogen; David Case; Christopher Roark; Samy Youssef; Joshua Seinfeld
Journal:  J Pers Med       Date:  2022-05-20

3.  Association Between Beta-Blocker or Statin Drug Use and the Risk of Hemorrhage From Cerebral Cavernous Malformations.

Authors:  Susanna M Zuurbier; Charlotte R Hickman; Leon A Rinkel; Rebecca Berg; Ulrich Sure; Rustam Al-Shahi Salman
Journal:  Stroke       Date:  2022-04-12       Impact factor: 10.170
  3 in total

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