Literature DB >> 31642866

Association of Cardiac Rehabilitation With Decreased Hospitalization and Mortality Risk After Cardiac Valve Surgery.

Devin K Patel1, Meredith S Duncan1, Ashish S Shah2, Brian R Lindman1, Robert A Greevy3, Patrick D Savage4, Mary A Whooley5, Michael E Matheny6, Matthew S Freiberg1, Justin M Bachmann1.   

Abstract

Importance: National guidelines recommend cardiac rehabilitation (CR) after cardiac valve surgery, and CR is covered by Medicare for this indication. However, few data exist regarding current CR enrollment after valve surgery. Objective: To characterize CR enrollment after cardiac valve surgery and its association with outcomes, including hospitalizations and mortality. Design, Setting, and Participants: This cohort study of patients undergoing valve surgery was conducted in calendar year 2014, with follow-up through 2015. The study included all fee-for-service Medicare beneficiaries undergoing open cardiac valve surgery in 2014. Patients identified by inpatient diagnosis codes for open aortic, mitral, tricuspid, and pulmonary valve surgery were included. Data analysis occurred from January 2018 to March 2019. Exposures: Logistic regression was used to evaluate sociodemographic and clinical factors associated with CR enrollment. Main Outcomes and Measures: We used Andersen-Gill models to evaluate the association of CR enrollment with 1-year hospitalization risk and Cox regression models to evaluate the association of CR enrollment with 1-year mortality risk.
Results: A total of 41 369 Medicare beneficiaries (median [interquartile range] age, 73 [68-79] years; 16 935 [40.9%] female) underwent open valve surgery in the United States in 2014. Fewer than half of patients (17 855 [43.2%]) who had valve surgery enrolled in CR programs. Several racial/ethnic groups had lower odds of enrolling in CR programs after valve surgery compared with white patients, including Asian patients (odds ratio [OR], 0.36 [95% CI, 0.28-0.47]), black patients (OR, 0.60 [95% CI, 0.54-0.67]), and Hispanic patients (OR, 0.36 [95% CI, 0.28-0.46]). Patients undergoing concomitant coronary artery bypass grafting had higher odds of CR enrollment (OR, 1.26 [95% CI, 1.20-1.31]) than those without the concomitant coronary artery bypass graft procedure, as did patients in the Midwest census region (OR, 2.40 [95% CI, 2.28-2.54]) compared with those in the South (reference). Cardiac rehabilitation enrollment was associated with fewer hospitalizations within 1 year of discharge (hazard ratio, 0.66 [95% CI, 0.63-0.69] after multivariable adjustment). Enrollment was also associated with a 4.2% absolute decrease in 1-year mortality risk (hazard ratio, 0.39 [95% CI, 0.35-0.44] after multivariable adjustment). Conclusions and Relevance: Fewer than half of Medicare beneficiaries undergoing cardiac valve surgery enroll in CR programs, and there are marked racial/ethnic disparities among those that do. Cardiac rehabilitation is associated with decreased 1-year cumulative hospitalization and mortality risk after valve surgery. These results invite further study on barriers to CR enrollment in this population.

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Year:  2019        PMID: 31642866      PMCID: PMC6813589          DOI: 10.1001/jamacardio.2019.4032

Source DB:  PubMed          Journal:  JAMA Cardiol            Impact factor:   14.676


  23 in total

Review 1.  Immortal time bias in pharmaco-epidemiology.

Authors:  Samy Suissa
Journal:  Am J Epidemiol       Date:  2007-12-03       Impact factor: 4.897

2.  Cardiac rehabilitation is associated with reduced long-term mortality in patients undergoing combined heart valve and CABG surgery.

Authors:  Kashish Goel; Quinn R Pack; Brian Lahr; Kevin L Greason; Francisco Lopez-Jimenez; Ray W Squires; Zixin Zhang; Randal J Thomas
Journal:  Eur J Prev Cardiol       Date:  2013-11-21       Impact factor: 7.804

3.  Assessing the sensitivity of regression results to unmeasured confounders in observational studies.

Authors:  D Y Lin; B M Psaty; R A Kronmal
Journal:  Biometrics       Date:  1998-09       Impact factor: 2.571

4.  Frail patients are at increased risk for mortality and prolonged institutional care after cardiac surgery.

Authors:  Dana H Lee; Karen J Buth; Billie-Jean Martin; Alexandra M Yip; Gregory M Hirsch
Journal:  Circulation       Date:  2010-02-16       Impact factor: 29.690

5.  Use of the landmark method to address immortal person-time bias in comparative effectiveness research: a simulation study.

Authors:  Xiaojuan Mi; Bradley G Hammill; Lesley H Curtis; Edward Chia-Cheng Lai; Soko Setoguchi
Journal:  Stat Med       Date:  2016-06-27       Impact factor: 2.373

6.  2018 ACC/AHA Clinical Performance and Quality Measures for Cardiac Rehabilitation: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures.

Authors:  Randal J Thomas; Gary Balady; Gaurav Banka; Theresa M Beckie; Jensen Chiu; Sana Gokak; P Michael Ho; Steven J Keteyian; Marjorie King; Karen Lui; Quinn Pack; Bonnie K Sanderson; Tracy Y Wang
Journal:  J Am Coll Cardiol       Date:  2018-03-29       Impact factor: 24.094

7.  Participation in cardiac rehabilitation and survival after coronary artery bypass graft surgery: a community-based study.

Authors:  Quinn R Pack; Kashish Goel; Brian D Lahr; Kevin L Greason; Ray W Squires; Francisco Lopez-Jimenez; Zixin Zhang; Randal J Thomas
Journal:  Circulation       Date:  2013-07-08       Impact factor: 29.690

8.  Relationship between cardiac rehabilitation and long-term risks of death and myocardial infarction among elderly Medicare beneficiaries.

Authors:  Bradley G Hammill; Lesley H Curtis; Kevin A Schulman; David J Whellan
Journal:  Circulation       Date:  2009-12-21       Impact factor: 29.690

9.  Survey Reported Participation in Cardiac Rehabilitation and Survival After Mitral or Aortic Valve Surgery.

Authors:  Quinn R Pack; Brian D Lahr; Ray W Squires; Francisco Lopez-Jimenez; Kevin L Greason; Hector I Michelena; Kashish Goel; Randal J Thomas
Journal:  Am J Cardiol       Date:  2016-04-05       Impact factor: 2.778

10.  National Trends and Outcomes in Isolated Tricuspid Valve Surgery.

Authors:  Chad J Zack; Erin A Fender; Pranav Chandrashekar; Yogesh N V Reddy; Courtney E Bennett; John M Stulak; Virginia M Miller; Rick A Nishimura
Journal:  J Am Coll Cardiol       Date:  2017-12-19       Impact factor: 24.094

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  11 in total

1.  Strengthening the Evidence for Cardiac Rehabilitation Benefits.

Authors:  Randal J Thomas; LaPrincess C Brewer
Journal:  JAMA Cardiol       Date:  2019-12-01       Impact factor: 14.676

Review 2.  The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 6: Sex- and Gender-Specific Diagnosis and Treatment.

Authors:  Monica Parry; Harriette G C Van Spall; Kerri-Anne Mullen; Sharon L Mulvagh; Christine Pacheco; Tracey J F Colella; Marie-Annick Clavel; Shahin Jaffer; Heather J A Foulds; Jasmine Grewal; Marsha Hardy; Jennifer A D Price; Anna L E Levinsson; Christine A Gonsalves; Colleen M Norris
Journal:  CJC Open       Date:  2022-04-19

3.  Carbon monoxide monitoring to objectively measure smoking status in cardiac rehabilitation.

Authors:  Diann E Gaalema; Blair Yant; Sherrie Khadanga; Patrick D Savage; Jason L Rengo; Philip A Ades
Journal:  Health Psychol       Date:  2022-04-07       Impact factor: 5.556

Review 4.  Disparities in the Use of Cardiac Rehabilitation in African Americans.

Authors:  Lena Mathews; Ofure Akhiwu; Monica Mukherjee; Roger S Blumenthal; Kunihiro Matsushita; Chiadi E Ndumele
Journal:  Curr Cardiovasc Risk Rep       Date:  2022-05-07

Review 5.  A Review of Disparities in Cardiac Rehabilitation: EVIDENCE, DRIVERS, AND SOLUTIONS.

Authors:  Lena Mathews; LaPrincess C Brewer
Journal:  J Cardiopulm Rehabil Prev       Date:  2021-11-01       Impact factor: 2.081

6.  Exercise-based cardiac rehabilitation for adults after heart valve surgery.

Authors:  Lizette N Abraham; Kirstine L Sibilitz; Selina K Berg; Lars H Tang; Signe S Risom; Jane Lindschou; Rod S Taylor; Britt Borregaard; Ann-Dorthe Zwisler
Journal:  Cochrane Database Syst Rev       Date:  2021-05-07

7.  Implementation of an Appointment-Based Cardiac Rehabilitation Approach: A Single-Center Experience.

Authors:  Catherine X Wright; Sean Fournier; Yanhong Deng; Can Meng; Susan Hiller; Joyce M Oen-Hsiao; Rachel P Dreyer
Journal:  J Am Heart Assoc       Date:  2022-05-02       Impact factor: 6.106

8.  Priorities for Patient-Centered Research in Valvular Heart Disease: A Report From the National Heart, Lung, and Blood Institute Working Group.

Authors:  Brian R Lindman; Suzanne V Arnold; Rodrigo Bagur; Lindsay Clarke; Megan Coylewright; Frank Evans; Judy Hung; Sandra B Lauck; Susan Peschin; Vandana Sachdev; Lisa M Tate; Jason H Wasfy; Catherine M Otto
Journal:  J Am Heart Assoc       Date:  2020-04-24       Impact factor: 5.501

9.  The impact of additional resistance and balance training in exercise-based cardiac rehabilitation in older patients after valve surgery or intervention: randomized control trial.

Authors:  Egle Tamulevičiūtė-Prascienė; Aurelija Beigienė; Mark James Thompson; Kristina Balnė; Raimondas Kubilius; Birna Bjarnason-Wehrens
Journal:  BMC Geriatr       Date:  2021-01-07       Impact factor: 4.070

10.  Effect of a pragmatic home-based mobile health exercise intervention after transcatheter aortic valve replacement: a randomized pilot trial.

Authors:  Brian R Lindman; Linda D Gillam; Megan Coylewright; Frederick G P Welt; Sammy Elmariah; Stephanie A Smith; David A McKeel; Natalie Jackson; Kush Mukerjee; Harrison Cloud; Narden Hanna; Jenelle Purpura; Hannah Ellis; Vong Martinez; Alexandra M Selberg; Shi Huang; Frank E Harrell
Journal:  Eur Heart J Digit Health       Date:  2021-02-04
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