Literature DB >> 31642717

Pharmaceutical implants: classification, limitations and therapeutic applications.

Zahra Mohtashami1, Zahra Esmaili1, Molood Alsadat Vakilinezhad1, Ehsan Seyedjafari2, Hamid Akbari Javar1.   

Abstract

Controlled/sustained delivery systems have been developed rapidly which show the ability to overcome the obstacles of traditional delivery systems. Daily development of biomedical and biomaterial sciences has brought more attention to the implantable delivery systems. As a result, these systems have found their position in the medical field since they were introduced. The advances in the polymeric science along with the other fields, make the production of a wide variety of implantable systems, possible. The influence of these systems in medical field could not be denied Here', the pharmaceutical applications which have been mostly focused on, are discussed. Since these systems have proven to be beneficial, researchers are trying to adjust their defects to the desired properties. Doing so, the path that implantable delivery systems have crossed so far should be studied, and that's the aim of this review. In the present report, the advantages of these systems in chemotherapeutic, contraceptive, neuropsychology, pain management, peptide delivery, ocular delivery, cardiovascular, orthopedic, and dental fields have been evaluated.

Entities:  

Keywords:  Pharmaceutical implants; chemotherapeutical implants; contraceptive implants; ocular delivery; pain management; peptide delivery

Mesh:

Substances:

Year:  2019        PMID: 31642717     DOI: 10.1080/10837450.2019.1682607

Source DB:  PubMed          Journal:  Pharm Dev Technol        ISSN: 1083-7450            Impact factor:   3.133


  3 in total

1.  Tissue-reactive drugs enable materials-free local depots.

Authors:  Sharda Pandit; Sandeep Palvai; Nicholas P Massaro; Joshua G Pierce; Yevgeny Brudno
Journal:  J Control Release       Date:  2022-01-22       Impact factor: 9.776

2.  Development of Porous Polyurethane Implants Manufactured via Hot-Melt Extrusion.

Authors:  Ioannis Koutsamanis; Martin Spoerk; Florian Arbeiter; Simone Eder; Eva Roblegg
Journal:  Polymers (Basel)       Date:  2020-12-10       Impact factor: 4.329

Review 3.  Implantable Drug Delivery Systems and Foreign Body Reaction: Traversing the Current Clinical Landscape.

Authors:  Alexey Fayzullin; Alesia Bakulina; Karen Mikaelyan; Anatoly Shekhter; Anna Guller
Journal:  Bioengineering (Basel)       Date:  2021-12-09
  3 in total

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