| Literature DB >> 3164248 |
M Tiainen1, L Tammilehto, K Mattson, S Knuutila.
Abstract
Cytogenetic studies were performed on tumor cells from specimens of 30 consecutive patients with malignant pleural mesothelioma. Metaphases for chromosomal G-banding analyses were obtained from 27 of these patients. Clonal abnormalities were detected in 19 patients. Karyotype findings were complex and heterogeneous: aneuploidy, polyploidy, structural abnormalities, and several subclones were seen. The most frequent chromosomal abnormalities were polysomy or partial polysomy 7, monosomy or partial monosomy 22, and rearrangements involving breakpoints at 1p11-22.Entities:
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Year: 1988 PMID： 3164248 DOI： 10.1016/0165-4608(88)90035-0
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608