Literature DB >> 31642458

Type III-C rotaxane dendrimers: synthesis, dual size modulation and in vivo evaluation.

Chak-Shing Kwan1, Tao Wang1, Min Li2, Albert S C Chan3, Zongwei Cai1, Ken Cham-Fai Leung1.   

Abstract

Type III-C rotaxane dendrimers were synthesized by a divergent approach. Dual shuttling behavior and size modulation were observed from non-methylated/methylated rotaxane dendrimers under the same external stimuli. The biological distribution of dendrimers in C57BL/6J mice determined by MALDI-TOF-MS shows predominant accumulation in the spleen and liver. Drug encapsulations with chlorambucil and lithocholic acid were demonstrated.

Entities:  

Year:  2019        PMID: 31642458     DOI: 10.1039/c9cc06200a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

Review 1.  Rotaxane nanomachines in future molecular electronics.

Authors:  Peiqiao Wu; Bhushan Dharmadhikari; Prabir Patra; Xingguo Xiong
Journal:  Nanoscale Adv       Date:  2022-06-24
  1 in total

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