Anthony H Lequerica1,2, Erica Weber1,2, Marcel P Dijkers3, Kristen Dams-O'Connor3,4, Stephanie A Kolakowsky-Hayner3, Kathleen R Bell5, Tamara Bushnik6, Yelena Goldin7,8, Flora M Hammond9,10. 1. Center for Traumatic Brain Injury Research, Kessler Foundation, East Hanover, NJ, USA. 2. Department of Physical Medicine and Rehabilitation, Rutgers New Jersey Medical School, Newark, NJ, USA. 3. Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. 4. Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. 5. Department of Physical Medicine and Rehabilitation, University of Texas Southwestern, Dallas, TX, USA. 6. Rusk Rehabilitation, NYU Langone Health, New York, NY, USA. 7. Cognitive Rehabilitation Department, JFK-Johnson Rehabilitation Institute, Edison, NJ, USA. 8. Department of Physical Medicine and Rehabilitation, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA. 9. Department of Physical Medicine and Rehabilitation, Indiana University School of Medicine, West Lafayette, IN, USA. 10. Rehabilitation Hospital of Indiana, Indianapolis, IN, USA.
Abstract
Objective: To examine the factors associated with the remission of insomnia by examining a sample of individuals who had insomnia within the first two years after traumatic brain injury (TBI) and assessing their status at a secondary time point.Design and Methods: Secondary data analysis from a multicenter longitudinal cohort study. A sample of 40 individuals meeting inclusion criteria completed a number of self-report scales measuring sleep/wake characteristics (Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Insomnia Severity Index, Sleep Hygiene Index), fatigue and depression (Multidimensional Assessment of Fatigue, Patient Health Questionnaire-9), and community participation (Participation Assessment with Recombined Tools-Objective). One cohort was followed at 1 and 2 years post-injury (n = 19) while a second cohort was followed at 2 and 5 years post-injury (n = 21). Results: Remission of insomnia was noted in 60% of the sample. Those with persistent insomnia had significantly higher levels of fatigue and depression at their final follow-up and poorer sleep hygiene across both follow-up time-points. A trend toward reduced community participation among those with persistent insomnia was also found. Conclusion: Individuals with persistent post-TBI insomnia had poorer psychosocial outcomes. The chronicity of post-TBI insomnia may be associated with sleep-related behaviors that serve as perpetuating factors.
Objective: To examine the factors associated with the remission of insomnia by examining a sample of individuals who had insomnia within the first two years after traumatic brain injury (TBI) and assessing their status at a secondary time point.Design and Methods: Secondary data analysis from a multicenter longitudinal cohort study. A sample of 40 individuals meeting inclusion criteria completed a number of self-report scales measuring sleep/wake characteristics (Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Insomnia Severity Index, Sleep Hygiene Index), fatigue and depression (Multidimensional Assessment of Fatigue, Patient Health Questionnaire-9), and community participation (Participation Assessment with Recombined Tools-Objective). One cohort was followed at 1 and 2 years post-injury (n = 19) while a second cohort was followed at 2 and 5 years post-injury (n = 21). Results: Remission of insomnia was noted in 60% of the sample. Those with persistent insomnia had significantly higher levels of fatigue and depression at their final follow-up and poorer sleep hygiene across both follow-up time-points. A trend toward reduced community participation among those with persistent insomnia was also found. Conclusion: Individuals with persistent post-TBI insomnia had poorer psychosocial outcomes. The chronicity of post-TBI insomnia may be associated with sleep-related behaviors that serve as perpetuating factors.
Authors: James M Trauer; Mary Y Qian; Joseph S Doyle; Shantha M W Rajaratnam; David Cunnington Journal: Ann Intern Med Date: 2015-08-04 Impact factor: 25.391
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Authors: Jackie L Gottshall; Vivian A Guedes; Josephine U Pucci; Daniel Brooks; Nora Watson; Phorum Sheth; Ainslee Gabriel; Sara Mithani; Jacqueline J Leete; Chen Lai; Bao-Xi Qu; Christina Devoto; Jessica M Gill; Kimbra Kenney; J Kent Werner Journal: Front Pharmacol Date: 2022-01-27 Impact factor: 5.810