Aim: To identify the difference in physical activity (PA) levels between individuals with and without cancer, and to estimate all-cause mortality associated with this difference. Methods: Current cancer, cancer survivor and cancer-free groups were identified from the UK Biobank. We used multivariate and Cox regression to estimate PA differences and association of PA with all-cause mortality. Results: Compared with the cancer-free individuals, participants in the two cancer groups had fewer minutes in moderate-to-vigorous PA per day in adjusted analyses. The PA difference was associated with higher mortality in the current cancer group. Conclusion: Patients with a history of cancer were less active than those without cancer, and PA is associated with increased mortality. PA improvement strategies in cancer patients must be explored.
Aim: To identify the difference in physical activity (PA) levels between individuals with and without cancer, and to estimate all-cause mortality associated with this difference. Methods: Current cancer, cancer survivor and cancer-free groups were identified from the UK Biobank. We used multivariate and Cox regression to estimate PA differences and association of PA with all-cause mortality. Results: Compared with the cancer-free individuals, participants in the two cancer groups had fewer minutes in moderate-to-vigorous PA per day in adjusted analyses. The PA difference was associated with higher mortality in the current cancer group. Conclusion:Patients with a history of cancer were less active than those without cancer, and PA is associated with increased mortality. PA improvement strategies in cancerpatients must be explored.
Entities:
Keywords:
UK Biobank; accelerometer; all-cause mortality; cancer; physical activity
Authors: Justin C Brown; Elizabeth Brighton; Nancy Campbell; Nadine J McCleary; Thomas A Abrams; James M Cleary; Peter C Enzinger; Kimmie Ng; Douglas Rubinson; Brian M Wolpin; Matthew B Yurgelun; Jeffrey A Meyerhardt Journal: BMJ Open Sport Exerc Med Date: 2022-05-30
Authors: Jessica McNeil; Mina Fahim; Chelsea R Stone; Rachel O'Reilly; Kerry S Courneya; Christine M Friedenreich Journal: J Cancer Surviv Date: 2021-03-22 Impact factor: 4.442
Authors: Joeri A J Douma; Maaike B de Beaufort; Caroline S Kampshoff; Saskia Persoon; Jorine A Vermaire; Mai J Chinapaw; Willem van Mechelen; Frans Nollet; Marie José Kersten; Jan H Smit; Irma M Verdonck-de Leeuw; Teatske M Altenburg; Laurien M Buffart Journal: Support Care Cancer Date: 2019-12-09 Impact factor: 3.603