Literature DB >> 3163723

Transforming growth factor-beta-like activity in tumors of the central nervous system.

W C Clark1, J Bressler.   

Abstract

Transforming growth factor type beta (TGF-beta) is a ubiquitous peptide with wide-ranging regulatory functions. This paper reports the initial isolation of TGF-beta activity from human glial and mesenchymally derived tumors and a human glial tumor cell line. While its physiological function at the molecular level is not yet defined, it is believed that this peptide plays a central role in the control of growth and transformation, with the exact role it plays being a function of the entire set of growth factors present in a given cell.

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Year:  1988        PMID： 3163723     DOI： 10.3171/jns.1988.68.6.0920

Source DB:  PubMed          Journal:  J Neurosurg        ISSN： 0022-3085            Impact factor:   5.115


  9 in total

1.  Immunophenotypic analysis of infiltrating leukocytes and microglia in an experimental rat glioma.

Authors:  T Morioka; T Baba; K L Black; W J Streit
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

Review 2.  Angiogenic growth factors in neural embryogenesis and neoplasia.

Authors:  D Zagzag
Journal:  Am J Pathol       Date:  1995-02       Impact factor: 4.307

3.  Brain Tumor Working Group Report on the 9th International Conference on Brain Tumor Research and Therapy. Organ System Program, National Cancer Institute.

Authors:  D F Deen; A Chiarodo; E A Grimm; J R Fike; M A Israel; L E Kun; V A Levin; L J Marton; R J Packer; A E Pegg
Journal:  J Neurooncol       Date:  1993-06       Impact factor: 4.130

4.  Immunocytochemical study of transforming growth factor expression in benign and malignant gliomas.

Authors:  V Samuels; J M Barrett; S Bockman; C G Pantazis; M B Allen
Journal:  Am J Pathol       Date:  1989-04       Impact factor: 4.307

5.  TM-1 cells from an established human malignant glioma cell line produce PDGF, TGF-alpha, and TGF-beta which cooperatively play a stimulatory role for an autocrine growth promotion.

Authors:  M Kurimoto; S Endo; K Arai; Y Horie; K Nogami; A Takaku
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

6.  A cell line of human malignant astrocytoma producing autocrine growth factor.

Authors:  K Arai; Y Horie; M Kurimoto; S Endoh; K Hiraga; A Takaku
Journal:  In Vitro Cell Dev Biol       Date:  1991-08

7.  A sequential cell kinetic study of meningioma cells in primary explant culture using bromodeoxyuridine.

Authors:  K Kharbanda; A K Karak; C Sarkar; A K Dinda; M Mathur; S Roy
Journal:  J Neurooncol       Date:  1993-05       Impact factor: 4.130

Review 8.  Recent developments on immunotherapy for brain cancer.

Authors:  Derek A Wainwright; Pragati Nigam; Bart Thaci; Mahua Dey; Maciej S Lesniak
Journal:  Expert Opin Emerg Drugs       Date:  2012-04-25       Impact factor: 4.191

9.  Transforming growth factor-beta activity is potentiated by heparin via dissociation of the transforming growth factor-beta/alpha 2-macroglobulin inactive complex.

Authors:  T A McCaffrey; D J Falcone; C F Brayton; L A Agarwal; F G Welt; B B Weksler
Journal:  J Cell Biol       Date:  1989-07       Impact factor: 10.539
  9 in total

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