Literature DB >> 3163241

Comparison of difloxacin, enoxacin, and cefazolin for the treatment of experimental Staphylococcus aureus endocarditis.

J A Boscia1, W D Kobasa, D Kaye.   

Abstract

This study compared difloxacin administered orally, enoxacin administered orally, and cefazolin administered intramuscularly for the treatment of experimental Staphylococcus aureus endocarditis. Difloxacin significantly reduced bacterial counts of vegetations compared with enoxacin. This study demonstrated that difloxacin was significantly more effective than enoxacin and as effective as cefazolin for the treatment of S. aureus endocarditis in rabbits.

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Year:  1988        PMID： 3163241      PMCID： PMC172148          DOI： 10.1128/AAC.32.2.262

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Chemotherapy of experimental streptococcal endocarditis. I. Comparison of commonly recommended prophylactic regimens.

Authors:  D T Durack; R G Petersdorf
Journal:  J Clin Invest       Date:  1973-03       Impact factor: 14.808

2.  Antibiotic synergism in enterococcal endocarditis.

Authors:  J Carrizosa; D Kaye
Journal:  J Lab Clin Med       Date:  1976-07

3.  Pefloxacin therapy for experimental endocarditis caused by methicillin-susceptible or methicillin-resistant strains of Staphylococcus aureus.

Authors:  P M Sullam; M G Täuber; C J Hackbarth; H F Chambers; K G Scott; M A Sande
Journal:  Antimicrob Agents Chemother       Date:  1985-05       Impact factor: 5.191

4.  Comparative evaluation of A-56619, A-56620, and nafcillin in the treatment of experimental Staphylococcus aureus osteomyelitis.

Authors:  J T Mader; L T Morrison; K R Adams
Journal:  Antimicrob Agents Chemother       Date:  1987-02       Impact factor: 5.191

5.  Difloxacin metabolism and pharmacokinetics in humans after single oral doses.

Authors:  G R Granneman; K M Snyder; V S Shu
Journal:  Antimicrob Agents Chemother       Date:  1986-11       Impact factor: 5.191

6.  Enoxacin compared with vancomycin for the treatment of experimental methicillin-resistant Staphylococcus aureus endocarditis.

Authors:  M Gilbert; J A Boscia; W D Kobasa; D Kaye
Journal:  Antimicrob Agents Chemother       Date:  1986-03       Impact factor: 5.191

7.  Efficacy of ciprofloxacin for experimental endocarditis caused by methicillin-susceptible or -resistant strains of Staphylococcus aureus.

Authors:  T C Carpenter; C J Hackbarth; H F Chambers; M A Sande
Journal:  Antimicrob Agents Chemother       Date:  1986-09       Impact factor: 5.191
  7 in total
  2 in total

1.  Disposition kinetics of difloxacin in rabbit after intravenous and intramuscular injection of Dicural.

Authors:  A M Abd El-Aty; A Goudah; M Ismail; M Shimoda
Journal:  Vet Res Commun       Date:  2005-05       Impact factor: 2.459

Review 2.  Evaluation of quinolones in experimental animal models of infections.

Authors:  W M Scheld
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-04       Impact factor: 3.267
  2 in total

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