| Literature DB >> 31631346 |
Spencer Dunaway1, Kelly Tyler2, Jessica Kaffenberger2.
Abstract
Vulvovaginal lichen planus (VVLP) is a debilitating disease that causes significant pain and psychological distress. Management is made difficult by the chronic course of the disease and its resistance to treatment. While topical steroids have been accepted as the first-line treatment, they fail to achieve symptomatic control in approximately 40% of patients. Second-line therapies include other topical treatments such as calcineurin inhibitors, systemic therapies including oral steroids, methotrexate, mycophenolate mofetil, biologics, and tacrolimus, and procedural options including surgery and dilation, photodynamic therapy, and ultrasound. This review provides an overview of the current treatments and explores the level of evidence supporting each of them.Entities:
Year: 2019 PMID: 31631346 DOI: 10.1111/ijd.14692
Source DB: PubMed Journal: Int J Dermatol ISSN: 0011-9059 Impact factor: 2.736