Literature DB >> 316295

[Experimental investigations of the aqueous humor and blood serum of rabbits following injection of tobramycin].

G Papapanos, A Petunis, X Karageorgiou.   

Abstract

In animal experiments the concentration of the antibiotic Tobramycin in the aqueous humor and blood serum following intramuscular and subconjunctival injections was tested by diffusion on agar plates. After intramuscular injections, only traces of Tobramycin were found in the aqueous humor, but a significantly higher concentration of the antibiotic was obtained by subconjunctival injections. The subconjunctival application of the antibiotic was well tolerated.

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Year:  1979        PMID： 316295     DOI： 10.1007/bf02387433

Source DB:  PubMed          Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol        ISSN： 0065-6100


  10 in total

1.  Penetration of tobramycin sulfate in the aqueous humor of the rabbit.

Authors:  M M Uwaydah; B M Faris
Journal:  Arch Ophthalmol       Date:  1976-07

2.  Penetration of antistaphylococcal antibiotics into the human eye.

Authors:  W A MacIlwaine; M A Sande; G L Mandell
Journal:  Am J Ophthalmol       Date:  1974-04       Impact factor: 5.258

3.  Simplified, accurate method for antibiotic assay of clinical specimens.

Authors:  J V Bennett; J L Brodie; E J Benner; W M Kirby
Journal:  Appl Microbiol       Date:  1966-03

4.  The effect of tobramycin on rabbit eyes.

Authors:  W D Purnell; S D McPherson
Journal:  Am J Ophthalmol       Date:  1974-04       Impact factor: 5.258

5.  Penetration of gentamicin. Administered intramuscularly and subconjunctivally into aqueous humor.

Authors:  K D Litwack; T Petit; B L Ohnson; B L Johnson
Journal:  Arch Ophthalmol       Date:  1969-11

6.  Penetration of gentamicin into the aqueous humor of human eyes.

Authors:  F P Furgiuele
Journal:  Am J Ophthalmol       Date:  1970-03       Impact factor: 5.258

7.  In vitro studies of tobramycin, an aminoglycoside antibiotic.

Authors:  J Dienstag; H C Neu
Journal:  Antimicrob Agents Chemother       Date:  1972-01       Impact factor: 5.191

8.  Evaluation of the in vitro activity of tobramycin as compared with that of gentamicin sulfate.

Authors:  W H Traub; E A Raymond
Journal:  Appl Microbiol       Date:  1972-01

9.  Clinical study of the use of the new aminoglycoside tobramycin for therapy of infections due to gram-negative bacteria.

Authors:  G Jaffe; W Ravreby; B R Meyers; S Z Hirschman
Journal:  Antimicrob Agents Chemother       Date:  1974-01       Impact factor: 5.191

10.  In vitro studies of tobramycin.

Authors:  G P Bodey; D Stewart
Journal:  Antimicrob Agents Chemother       Date:  1972-09       Impact factor: 5.191
  10 in total
  2 in total

1.  Ciprofloxacin concentration in the rabbit aqueous humor and vitreous following intravenous and subconjunctival administration.

Authors:  W Behrens-Baumann; J Martell
Journal:  Infection       Date:  1988       Impact factor: 3.553

2.  Azlocillin concentrations in human aqueous humor after intravenous and subconjunctival administration.

Authors:  W Behrens-Baumann; R Ansorg
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1983       Impact factor: 3.117
  2 in total

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