Literature DB >> 31626562

Targeting Proteases in Cystic Fibrosis Lung Disease. Paradigms, Progress, and Potential.

Michael C McKelvey1, Sinéad Weldon1, Daniel F McAuley2, Marcus A Mall3,4,5, Clifford C Taggart1.   

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Year:  2020        PMID： 31626562      PMCID： PMC6961750          DOI： 10.1164/rccm.201906-1190PP

Source DB:  PubMed          Journal:  Am J Respir Crit Care Med        ISSN： 1073-449X            Impact factor:   21.405


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  69 in total

Review 1.  Matrix metalloproteinases in lung: multiple, multifarious, and multifaceted.

Authors:  Kendra J Greenlee; Zena Werb; Farrah Kheradmand
Journal:  Physiol Rev       Date:  2007-01       Impact factor: 37.312

2.  Cathepsin G and neutrophil elastase play critical and nonredundant roles in lung-protective immunity against Streptococcus pneumoniae in mice.

Authors:  Ines Hahn; Anna Klaus; Ann-Kathrin Janze; Kathrin Steinwede; Nadine Ding; Jennifer Bohling; Christina Brumshagen; Hélène Serrano; Francis Gauthier; James C Paton; Tobias Welte; Ulrich A Maus
Journal:  Infect Immun       Date:  2011-09-12       Impact factor: 3.441

3.  Low anticoagulant heparin targets multiple sites of inflammation, suppresses heparin-induced thrombocytopenia, and inhibits interaction of RAGE with its ligands.

Authors:  Narayanam V Rao; Brian Argyle; Xiaoyu Xu; Paul R Reynolds; Jeanine M Walenga; Margaret Prechel; Glenn D Prestwich; Robert B MacArthur; Bradford B Walters; John R Hoidal; Thomas P Kennedy
Journal:  Am J Physiol Cell Physiol       Date:  2010-04-07       Impact factor: 4.249

4.  Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.

Authors:  Katherine B Hisert; Sonya L Heltshe; Christopher Pope; Peter Jorth; Xia Wu; Rachael M Edwards; Matthew Radey; Frank J Accurso; Daniel J Wolter; Gordon Cooke; Ryan J Adam; Suzanne Carter; Brenda Grogan; Janice L Launspach; Seamas C Donnelly; Charles G Gallagher; James E Bruce; David A Stoltz; Michael J Welsh; Lucas R Hoffman; Edward F McKone; Pradeep K Singh
Journal:  Am J Respir Crit Care Med       Date:  2017-06-15       Impact factor: 21.405

5.  Doxycycline improves clinical outcomes during cystic fibrosis exacerbations.

Authors:  Xin Xu; Tarek Abdalla; Preston E Bratcher; Patricia L Jackson; Gina Sabbatini; J Michael Wells; Xiang-Yang Lou; Rebecca Quinn; J Edwin Blalock; J P Clancy; Amit Gaggar
Journal:  Eur Respir J       Date:  2017-04-05       Impact factor: 16.671

6.  Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis.

Authors:  A Susanne Dittrich; Iris Kühbandner; Stefanie Gehrig; Verena Rickert-Zacharias; Matthew Twigg; Sabine Wege; Clifford C Taggart; Felix Herth; Carsten Schultz; Marcus A Mall
Journal:  Eur Respir J       Date:  2018-03-29       Impact factor: 16.671

7.  Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase-3.

Authors:  M Padrines; M Wolf; A Walz; M Baggiolini
Journal:  FEBS Lett       Date:  1994-09-26       Impact factor: 4.124

8.  VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.

Authors:  Dominic Keating; Gautham Marigowda; Lucy Burr; Cori Daines; Marcus A Mall; Edward F McKone; Bonnie W Ramsey; Steven M Rowe; Laura A Sass; Elizabeth Tullis; Charlotte M McKee; Samuel M Moskowitz; Sarah Robertson; Jessica Savage; Christopher Simard; Fredrick Van Goor; David Waltz; Fengjuan Xuan; Tim Young; Jennifer L Taylor-Cousar
Journal:  N Engl J Med       Date:  2018-10-18       Impact factor: 91.245

9.  Linkage of neutrophil serine proteases and decreased surfactant protein-A (SP-A) levels in inflammatory lung disease.

Authors:  F Rubio; J Cooley; F J Accurso; E Remold-O'Donnell
Journal:  Thorax       Date:  2004-04       Impact factor: 9.139

10.  Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S.

Authors:  Silke Haerteis; Matteus Krappitz; Marko Bertog; Annabel Krappitz; Vera Baraznenok; Ian Henderson; Erik Lindström; Jane E Murphy; Nigel W Bunnett; Christoph Korbmacher
Journal:  Pflugers Arch       Date:  2012-08-05       Impact factor: 3.657
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  17 in total

1.  CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium.

Authors:  Clarissa Braccia; Josie A Christopher; Oliver M Crook; Lisa M Breckels; Rayner M L Queiroz; Nara Liessi; Valeria Tomati; Valeria Capurro; Tiziano Bandiera; Simona Baldassari; Nicoletta Pedemonte; Kathryn S Lilley; Andrea Armirotti
Journal:  Cells       Date:  2022-06-16       Impact factor: 7.666

2.  Polysulfated Hyaluronan GlycoMira-1111 Inhibits Elastase and Improves Rheology in Cystic Fibrosis Sputum.

Authors:  Apparao B Kummarapurugu; Shuo Zheng; Abigail Pulsipher; Justin R Savage; Jonathan Ma; Bruce K Rubin; Thomas P Kennedy; Judith A Voynow
Journal:  Am J Respir Cell Mol Biol       Date:  2021-02       Impact factor: 6.914

Review 3.  Alpha-1 Antitrypsin-A Target for MicroRNA-Based Therapeutic Development for Cystic Fibrosis.

Authors:  Alison M D Hunt; Arlene M A Glasgow; Hilary Humphreys; Catherine M Greene
Journal:  Int J Mol Sci       Date:  2020-01-28       Impact factor: 5.923

Review 4.  Neutrophil Adaptations upon Recruitment to the Lung: New Concepts and Implications for Homeostasis and Disease.

Authors:  Vincent D Giacalone; Camilla Margaroli; Marcus A Mall; Rabindra Tirouvanziam
Journal:  Int J Mol Sci       Date:  2020-01-28       Impact factor: 5.923

5.  Spelunking in Sputum: Single-Cell RNA Sequencing Sheds New Insights into Cystic Fibrosis.

Authors:  Naoki Iwanaga; Jay K Kolls
Journal:  Am J Respir Crit Care Med       Date:  2020-11-15       Impact factor: 21.405

Review 6.  Airway Inflammation and Host Responses in the Era of CFTR Modulators.

Authors:  Karen Keown; Ryan Brown; Declan F Doherty; Claire Houston; Michael C McKelvey; Shannice Creane; Dermot Linden; Daniel F McAuley; Joseph C Kidney; Sinéad Weldon; Damian G Downey; Clifford C Taggart
Journal:  Int J Mol Sci       Date:  2020-09-02       Impact factor: 5.923

Review 7.  SP-A and SP-D: Dual Functioning Immune Molecules With Antiviral and Immunomodulatory Properties.

Authors:  Alastair Watson; Jens Madsen; Howard William Clark
Journal:  Front Immunol       Date:  2021-01-19       Impact factor: 7.561

Review 8.  Proteases, Mucus, and Mucosal Immunity in Chronic Lung Disease.

Authors:  Michael C McKelvey; Ryan Brown; Sinéad Ryan; Marcus A Mall; Sinéad Weldon; Clifford C Taggart
Journal:  Int J Mol Sci       Date:  2021-05-09       Impact factor: 5.923

Review 9.  Glycosaminoglycans as Multifunctional Anti-Elastase and Anti-Inflammatory Drugs in Cystic Fibrosis Lung Disease.

Authors:  Judith A Voynow; Shuo Zheng; Apparao B Kummarapurugu
Journal:  Front Pharmacol       Date:  2020-07-08       Impact factor: 5.810

Review 10.  Role of Cystic Fibrosis Bronchial Epithelium in Neutrophil Chemotaxis.

Authors:  Giulio Cabrini; Alessandro Rimessi; Monica Borgatti; Ilaria Lampronti; Alessia Finotti; Paolo Pinton; Roberto Gambari
Journal:  Front Immunol       Date:  2020-08-04       Impact factor: 7.561
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