Literature DB >> 31626247

Drug orientations within statin-loaded lipoprotein nanoparticles by 19F solid-state NMR.

Sophie Lau1, Naomi Stanhope1, John Griffin1, Eleri Hughes1, David A Middleton1.   

Abstract

NMR measurements of 19F chemical shift anisotropy and 1H-19F dipolar couplings provide unprecedented information on the molecular orientations of two fluorine-containing statin drugs within the heterogeneous environment of reconstituted high-density lipoprotein (rHDL) nanoparticles, a drug delivery system under clinical investigation.

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Year:  2019        PMID: 31626247     DOI: 10.1039/c9cc05344a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  1 in total

1.  19 F Solid-State NMR and Vibrational Raman Characterization of Corticosteroid Drug-Lipid Membrane Interactions.

Authors:  Bethany Mapley; David Townsend; John Griffin; Lorna Ashton; David A Middleton
Journal:  Chempluschem       Date:  2021-11-02       Impact factor: 3.210

  1 in total

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