OBJECTIVES: To study thyroid alterations in health care workers according to their working status. METHODS: We performed a retrospective study including 299 hospital employers who underwent in 2016 a periodic health surveillance checks in the Service of Occupational Medicine. According to the working status (rotating night-shift working [no. 160] vs day-working [no. 139]), we divided participant's clinical, anthropometric, and thyroid echographic characteristics. RESULTS: Respect to day workers, rotating night-shift workers were slightly older and more frequently male whereas had similar thyroid stimulating hormone, Ft3, Ft4 levels, and autoimmunity (anti-TPO levels more than 30). Univariate and multivariate regression analysis revealed that rotating night shift work is associated to a significantly increased number of thyroid nodules. CONCLUSIONS: This retrospective report suggests that the alteration in the molecular clocks typical of rotating night-shift workers harbors a higher risk of thyroid nodule development compared with diurnal workers. This novel result deserves replication in larger cohorts since thyroid nodules not rarely can represent thyroid cancers.
OBJECTIVES: To study thyroid alterations in health care workers according to their working status. METHODS: We performed a retrospective study including 299 hospital employers who underwent in 2016 a periodic health surveillance checks in the Service of Occupational Medicine. According to the working status (rotating night-shift working [no. 160] vs day-working [no. 139]), we divided participant's clinical, anthropometric, and thyroid echographic characteristics. RESULTS: Respect to day workers, rotating night-shift workers were slightly older and more frequently male whereas had similar thyroid stimulating hormone, Ft3, Ft4 levels, and autoimmunity (anti-TPO levels more than 30). Univariate and multivariate regression analysis revealed that rotating night shift work is associated to a significantly increased number of thyroid nodules. CONCLUSIONS: This retrospective report suggests that the alteration in the molecular clocks typical of rotating night-shift workers harbors a higher risk of thyroid nodule development compared with diurnal workers. This novel result deserves replication in larger cohorts since thyroid nodules not rarely can represent thyroid cancers.
Authors: Jennifer E Kyle; Lisa M Bramer; Daniel Claborne; Kelly G Stratton; Kent J Bloodsworth; Justin G Teeguarden; Shobhan Gaddameedhi; Thomas O Metz; Hans P A Van Dongen Journal: Nat Sci Sleep Date: 2022-05-21
Authors: Luca Coppeta; Cristiana Ferrari; Marco Trabucco Aurilio; Gianluigi Ferrazza; Andrea Magrini; Stefano Rizza Journal: Int J Environ Res Public Health Date: 2022-07-20 Impact factor: 4.614
Authors: S Rizza; L Coppeta; S Grelli; G Ferrazza; M Chiocchi; G Vanni; O C Bonomo; A Bellia; M Andreoni; A Magrini; M Federici Journal: J Endocrinol Invest Date: 2020-08-27 Impact factor: 4.256