Literature DB >> 31626045

Is Doxycycline Appropriate for Routine Treatment of Young Children With Erythema Migrans?

Gary P Wormser1, Franc Strle2, Eugene D Shapiro3.   

Abstract

The frequency of permanent staining of teeth of young children from doxycycline is thought to be lower than from older tetracyclines, but the precise risk is uncertain. Until more definitive data become available, doxycycline should not be used routinely to treat young children with erythema migrans, a manifestation of Lyme disease for which other antimicrobials are highly effective.

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Year:  2019        PMID： 31626045      PMCID： PMC6814264          DOI： 10.1097/INF.0000000000002453

Source DB:  PubMed          Journal:  Pediatr Infect Dis J        ISSN： 0891-3668            Impact factor:   2.129


  7 in total

1.  Absence of tooth staining with doxycycline treatment in young children.

Authors:  Benjamin Volovitz; Ronit Shkap; Jacob Amir; Shlomo Calderon; Izhak Varsano; Moshe Nussinovitch
Journal:  Clin Pediatr (Phila)       Date:  2007-03       Impact factor: 1.168

2.  Some pharmacokinetic aspects of doxycycline metabolism in man.

Authors:  M Schach von Wittenau
Journal:  Chemotherapia (Basel)       Date:  1968

3.  The clinical assessment, treatment, and prevention of lyme disease, human granulocytic anaplasmosis, and babesiosis: clinical practice guidelines by the Infectious Diseases Society of America.

Authors:  Gary P Wormser; Raymond J Dattwyler; Eugene D Shapiro; John J Halperin; Allen C Steere; Mark S Klempner; Peter J Krause; Johan S Bakken; Franc Strle; Gerold Stanek; Linda Bockenstedt; Durland Fish; J Stephen Dumler; Robert B Nadelman
Journal:  Clin Infect Dis       Date:  2006-10-02       Impact factor: 9.079

4.  No visible dental staining in children treated with doxycycline for suspected Rocky Mountain Spotted Fever.

Authors:  Suzanne R Todd; F Scott Dahlgren; Marc S Traeger; Eugenio D Beltrán-Aguilar; Donald W Marianos; Charlene Hamilton; Jennifer H McQuiston; Joanna J Regan
Journal:  J Pediatr       Date:  2015-03-17       Impact factor: 4.406

Review 5.  How safe is doxycycline for young children or for pregnant or breastfeeding women?

Authors:  Gary P Wormser; Ronald P Wormser; Franc Strle; Ronnie Myers; Burke A Cunha
Journal:  Diagn Microbiol Infect Dis       Date:  2018-10-04       Impact factor: 2.803

6.  Lyme disease in children in southeastern Connecticut. Pediatric Lyme Disease Study Group.

Authors:  M A Gerber; E D Shapiro; G S Burke; V J Parcells; G L Bell
Journal:  N Engl J Med       Date:  1996-10-24       Impact factor: 91.245

7.  Tetracycline-induced tooth changes.4. Discoloration and hypoplasia induced by tetracycline analogues.

Authors:  H A McIntosh; E Storey
Journal:  Med J Aust       Date:  1970-01-17       Impact factor: 7.738
  7 in total
  1 in total

Review 1.  Lyme Carditis: From Pathophysiology to Clinical Management.

Authors:  Cinzia Radesich; Eva Del Mestre; Kristen Medo; Giancarlo Vitrella; Paolo Manca; Mario Chiatto; Matteo Castrichini; Gianfranco Sinagra
Journal:  Pathogens       Date:  2022-05-15
  1 in total

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