Literature DB >> 31625522

5 Fluorouracil-loaded biosynthesised gold nanoparticles for the in vitro treatment of human pancreatic cancer cell.

Senthil Kumar Chinnaiyan1, Agnes Mary Soloman1, Ramesh Kannan Perumal1, Arun Gopinath1, Madhan Balaraman2.   

Abstract

In this study, green synthesis of gold nanoparticles (AuNPs) was performed by a sunlight irradiation method using the Borassus flabellifer fruit extract as a reducing agent. 5-Fluorouracil (5-FU)-loaded GG capped AuNPs (5FU-G-AuNPs) was prepared. The nanoparticles was further characterised by UV-visible spectra, particle size analysis, zeta potential, SAED, HRTEM, and XRD. The MTT assay results showed the suitability 5-FU-G-AuNPs. In this study, 5-FU-G-AuNPs exhibited potential cytotoxic and apoptotic effects on (MiaPaCa-2) cell line.

Entities:  

Mesh:

Substances:

Year:  2019        PMID: 31625522      PMCID: PMC8676362          DOI: 10.1049/iet-nbt.2019.0007

Source DB:  PubMed          Journal:  IET Nanobiotechnol        ISSN: 1751-8741            Impact factor:   1.847


  20 in total

1.  Facile synthesis of robust and biocompatible gold nanoparticles.

Authors:  Hongje Jang; Young-Kwan Kim; Soo-Ryoon Ryoo; Mi-Hee Kim; Dal-Hee Min
Journal:  Chem Commun (Camb)       Date:  2009-11-16       Impact factor: 6.222

2.  Green synthesis of polysaccharide/gold nanoparticle nanocomposite: an efficient ammonia sensor.

Authors:  Sadanand Pandey; Gopal K Goswami; Karuna K Nanda
Journal:  Carbohydr Polym       Date:  2013-01-16       Impact factor: 9.381

3.  Risk factors for pancreatic cancer in orientals.

Authors:  C T Lee; F Y Chang; S D Lee
Journal:  J Gastroenterol Hepatol       Date:  1996-05       Impact factor: 4.029

4.  Apoptotic activity of 5-fluorouracil in breast cancer cells transformed by low doses of ionizing α-particle radiation.

Authors:  Richard Ponce-Cusi; Gloria M Calaf
Journal:  Int J Oncol       Date:  2015-12-18       Impact factor: 5.650

5.  Gold nanoparticles: a revival in precious metal administration to patients.

Authors:  A S Thakor; J Jokerst; C Zavaleta; T F Massoud; S S Gambhir
Journal:  Nano Lett       Date:  2011-09-07       Impact factor: 11.189

Review 6.  Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancer.

Authors:  Lisa C Richardson; Lori A Pollack
Journal:  Nat Clin Pract Oncol       Date:  2005-01

7.  5-flourouracil loaded N,O-carboxymethyl chitosan nanoparticles as an anticancer nanomedicine for breast cancer.

Authors:  A Anitha; K P Chennazhi; S V Nair; R Jayakumar
Journal:  J Biomed Nanotechnol       Date:  2012-02       Impact factor: 4.099

8.  Rapid synthesis of gold nanoparticles with Cissus quadrangularis extract using microwave irradiation.

Authors:  S R Bhuvanasree; D Harini; Anantanarayanan Rajaram; Rama Rajaram
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2013-01-04       Impact factor: 4.098

9.  Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies.

Authors:  R Huxley; A Ansary-Moghaddam; A Berrington de González; F Barzi; M Woodward
Journal:  Br J Cancer       Date:  2005-06-06       Impact factor: 7.640

10.  Potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis.

Authors:  Priyabrata Mukherjee; Resham Bhattacharya; Nancy Bone; Yean K Lee; Chitta Ranjan Patra; Shanfeng Wang; Lichun Lu; Charla Secreto; Pataki C Banerjee; Michael J Yaszemski; Neil E Kay; Debabrata Mukhopadhyay
Journal:  J Nanobiotechnology       Date:  2007-05-08       Impact factor: 10.435

View more
  3 in total

Review 1.  Multifunctional Gold Nanoparticles in Cancer Diagnosis and Treatment.

Authors:  Yan Yang; Xi Zheng; Lu Chen; Xuefeng Gong; Hao Yang; Xingmei Duan; Yuxuan Zhu
Journal:  Int J Nanomedicine       Date:  2022-05-06

2.  Novel greenly synthesized titanium dioxide nanoparticles compared to liposomes in drug delivery: in vivo investigation on Ehrlich solid tumor model.

Authors:  Doaa A Abdel Fadeel; Magda S Hanafy; Nermeen A Kelany; Mohammed A Elywa
Journal:  Heliyon       Date:  2021-06-21

Review 3.  Surface-functionalised hybrid nanoparticles for targeted treatment of cancer.

Authors:  Hasnat Tariq; Syed Ali Imran Bokhari
Journal:  IET Nanobiotechnol       Date:  2020-09       Impact factor: 1.847

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.