Literature DB >> 3162073

Regional vasorelaxant selectivity of atrial natriuretic factor in isolated rabbit vessels.

E P Faison, P K Siegl, G Morgan, R J Winquist.   

Abstract

Synthetic atrial natriuretic factor (ANF) exhibited a marked selectivity in its ability to relax isolated rabbit arteries and veins. The aorta, renal and mesenteric arteries and the facial vein were the most sensitive vessels with the more distal arteries and most veins being relatively unresponsive to ANF. All preparations were effectively relaxed by sodium nitroprusside. ANF (up to 10(-7) M) failed to elicit any effect on isolated rabbit right atria or papillary muscles. The profound regional vasorelaxant selectivity of ANF may help to explain the hemodynamic effects of this substance in vivo.

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Year:  1985        PMID： 3162073     DOI： 10.1016/0024-3205(85)90599-5

Source DB:  PubMed          Journal:  Life Sci        ISSN： 0024-3205            Impact factor:   5.037


  11 in total

Review 1.  Atrial natriuretic factor: a hormone secreted by the heart.

Authors:  D D Macchia
Journal:  Pharm Weekbl Sci       Date:  1987-12-11

2.  Relationship between status of plasma atrial natriuretic peptide and heart rate variability in human subjects.

Authors:  Yuji Kasamaki; Yoichi Izumi; Yukio Ozawa; Masakatsu Ohta; Ayako Tano; Ichiro Watanabe; Atsushi Hirayama; Tomohiro Nakayama; Hiroshi Kawamura; Dilxat Himit; Maisumu Mahemuti; Akira Sezai
Journal:  Heart Vessels       Date:  2012-02-28       Impact factor: 2.037

Review 3.  The atrial natriuretic factor.

Authors:  J Genest
Journal:  Br Heart J       Date:  1986-10

4.  Venous responsiveness to atrial natriuretic factor in man.

Authors:  G A Ford; H G Eichler; B B Hoffman; T F Blaschke
Journal:  Br J Clin Pharmacol       Date:  1988-12       Impact factor: 4.335

5.  Effects of atrial natriuretic polypeptide and organic nitrates on levels of relaxation and cyclic nucleotide of canine coronary artery with and without endothelial injury.

Authors:  H Nakagawa; K Okumura; H Hashimoto; T Ito; K Ogawa; T Satake
Journal:  Heart Vessels       Date:  1988       Impact factor: 2.037

6.  Role of the L-arginine-NO pathway and of cyclic GMP in electrical field-induced noradrenaline release and vasoconstriction in the rat tail artery.

Authors:  B Bucher; S Ouedraogo; M Tschöpl; D Paya; J C Stoclet
Journal:  Br J Pharmacol       Date:  1992-12       Impact factor: 8.739

7.  Impaired cyclic nucleotide-mediated vasorelaxation may contribute to closure of the human umbilical artery after birth.

Authors:  S Renowden; D H Edwards; T M Griffith
Journal:  Br J Pharmacol       Date:  1992-06       Impact factor: 8.739

8.  Responses of monkey, rabbit and dog internal carotid arteries to atrial natriuretic factor.

Authors:  Y Kawai; T Ohhashi
Journal:  Experientia       Date:  1987-05-15

Review 9.  Atrial natriuretic peptide in the central nervous system of the rat.

Authors:  G Skofitsch; D M Jacobowitz
Journal:  Cell Mol Neurobiol       Date:  1988-12       Impact factor: 5.046

10.  Action of atrial natriuretic peptide (ANP) on dog cerebral arteries: evidence that neurogenic relaxation is not mediated by release of ANP.

Authors:  T Okamura; S Inoue; N Toda
Journal:  Br J Pharmacol       Date:  1989-08       Impact factor: 8.739
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