Literature DB >> 31620217

PROTAC Degradation of IRAK4 for the Treatment of Cancer.

Robert B Kargbo1.   

Abstract

Entities:  

Year:  2019        PMID： 31620217      PMCID： PMC6792152          DOI： 10.1021/acsmedchemlett.9b00423

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


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  3 in total

Review 1.  Recent advances in the discovery of small molecule inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4) as a therapeutic target for inflammation and oncology disorders.

Authors:  Divya Chaudhary; Shaughnessy Robinson; Donna L Romero
Journal:  J Med Chem       Date:  2014-12-05       Impact factor: 7.446

Review 2.  Interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitors: an updated patent review (2016-2018).

Authors:  William T McElroy
Journal:  Expert Opin Ther Pat       Date:  2019-03-29       Impact factor: 6.674

Review 3.  Pattern recognitions receptors in immunodeficiency disorders.

Authors:  Esameil Mortaz; Ian M Adcock; Payam Tabarsi; Ilad Alavi Darazam; Masoud Movassaghi; Johan Garssen; Hamidreza Jamaati; Aliakbar Velayati
Journal:  Eur J Pharmacol       Date:  2017-01-14       Impact factor: 4.432
  3 in total
  5 in total

Review 1.  The clinical and prognostic significance of CMTM6/PD-L1 in oncology.

Authors:  Mahmoud Mohammad Yaseen; Nizar Mohammad Abuharfeil; Homa Darmani
Journal:  Clin Transl Oncol       Date:  2022-03-12       Impact factor: 3.340

2.  A Genetic Screen for Human Genes Suppressing FUS Induced Toxicity in Yeast.

Authors:  Elliott Hayden; Shuzhen Chen; Abagail Chumley; Chenyi Xia; Quan Zhong; Shulin Ju
Journal:  G3 (Bethesda)       Date:  2020-06-01       Impact factor: 3.154

3.  Interleukin-1 receptor-associated kinase 4 as a potential biomarker: Overexpression predicts poor prognosis in patients with glioma.

Authors:  Jialin Wang; Binfeng Liu; Jiawei Yao; Zhendong Liu; Hongbo Wang; Bo Zhang; Xiaoyu Lian; Zhishuai Ren; Liyun Liu; Yanzheng Gao
Journal:  Oncol Lett       Date:  2021-02-03       Impact factor: 2.967

Review 4.  Discovery of E3 Ligase Ligands for Target Protein Degradation.

Authors:  Jaeseok Lee; Youngjun Lee; Young Mee Jung; Ju Hyun Park; Hyuk Sang Yoo; Jongmin Park
Journal:  Molecules       Date:  2022-10-02       Impact factor: 4.927

5.  Design of Novel IRAK4 Inhibitors Using Molecular Docking, Dynamics Simulation and 3D-QSAR Studies.

Authors:  Swapnil P Bhujbal; Weijie He; Jung-Mi Hah
Journal:  Molecules       Date:  2022-09-24       Impact factor: 4.927
  5 in total

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