Literature DB >> 31616123

Vascularized Osteochondral Grafts: Histologic Evaluation of Chondrocyte Viability with Viable Hyaline Nonfibrous Cartilage.

Brian B Freniere1, Aviram M Giladi2, Matthew L Iorio1,3.   

Abstract

Vascularized osteochondral flaps are used for challenging arthroplasties of the upper extremity. Little has been described regarding the biological outcomes of these flaps, specifically regarding the structure of the cartilage. The authors present a case of a 31-year-old patient undergoing medial femoral trochlea flap for proximal scaphoid arthroplasty in the setting of proximal pole avascular necrosis. The patient sustained a fracture that was treated by a headless compression screw and demonstrated provisional radiographic healing, but at late follow-up he had new fragmentation of the proximal pole. The medial femoral trochlea flap that comprised the proximal pole of the reconstructed scaphoid was found to have viable chondrocytes and regularly oriented hyaline cartilage on pathologic analysis 1 year postoperatively. The patient initially had relief of wrist pain and return to work but ultimately developed intractable pain requiring scaphoidectomy and midcarpal arthrodesis. Despite the failure of the procedure, the presence of histologically normal cartilage and viable chondrocytes in a vascularized osteochondral flap offers encouragement that this technique may provide a durable long-term solution for articular reconstruction. © Thieme Medical Publishers.

Entities:  

Keywords:  cartilage viability; medial femoral trochlea; osteochondral graft; scaphoid

Year:  2018        PMID: 31616123      PMCID: PMC6791798          DOI: 10.1055/s-0038-1675886

Source DB:  PubMed          Journal:  J Hand Microsurg        ISSN: 0974-3227


  10 in total

1.  Cutaneous angiosome territory of the medial femoral condyle osteocutaneous flap.

Authors:  Matthew L Iorio; Derek L Masden; James P Higgins
Journal:  J Hand Surg Am       Date:  2012-04-05       Impact factor: 2.230

2.  Vascularized medial femoral trochlea osteochondral flap reconstruction of advanced Kienböck disease.

Authors:  Heinz K Bürger; Christian Windhofer; Alexander J Gaggl; James P Higgins
Journal:  J Hand Surg Am       Date:  2014-05-22       Impact factor: 2.230

3.  The use of a single osteochondral autograft plug in the treatment of a large osteochondral lesion in the femoral condyle: an experimental study in sheep.

Authors:  Robert T Burks; Patrick E Greis; Steven Paul Arnoczky; Courtney Scher
Journal:  Am J Sports Med       Date:  2005-10-11       Impact factor: 6.202

4.  Nonvascularized Cartilage Grafts Versus Vascularized Cartilage Flaps: Comparison of Cartilage Quality 6 Months After Transfer.

Authors:  James P Higgins; Farzad Borumandi; Heinz K Bürger; Mehmet Emre Benlidayı; Anna Vasilyeva; Leman Sencar; Sait Polat; Alexander J Gaggl
Journal:  J Hand Surg Am       Date:  2017-10-14       Impact factor: 2.230

5.  Articular cartilage nutrition is mediated by subchondral bone: a long-term autograft study in baboons.

Authors:  T Malinin; E A Ouellette
Journal:  Osteoarthritis Cartilage       Date:  2000-11       Impact factor: 6.576

6.  Proximal scaphoid arthroplasty using the medial femoral trochlea flap.

Authors:  James P Higgins; Heinze K Burger
Journal:  J Wrist Surg       Date:  2013-08

7.  A morphologic, biochemical, and biomechanical assessment of short-term effects of osteochondral autograft plug transfer in an animal model.

Authors:  J G Lane; W L Tontz; S T Ball; J B Massie; A C Chen; W C Bae; M E Amiel; R L Sah; D Amiel
Journal:  Arthroscopy       Date:  2001-10       Impact factor: 4.772

8.  Vascularized medial femoral trochlea osteocartilaginous flap reconstruction of proximal pole scaphoid nonunions.

Authors:  Heinz K Bürger; Christian Windhofer; Alexander J Gaggl; James P Higgins
Journal:  J Hand Surg Am       Date:  2013-03-06       Impact factor: 2.230

Review 9.  Osteochondral Autograft Transplantation Surgery for Metacarpal Head Defects.

Authors:  Alison Kitay; Peter M Waters; Donald S Bae
Journal:  J Hand Surg Am       Date:  2016-01-21       Impact factor: 2.230

10.  Evaluation of subsidence, chondrocyte survival and graft incorporation following autologous osteochondral transplantation.

Authors:  Niels B Kock; Gerjon Hannink; Albert van Kampen; Nico Verdonschot; Job L C van Susante; Pieter Buma
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-09-09       Impact factor: 4.342

  10 in total

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