| Literature DB >> 31611366 |
Seong Mi Moon1, In Young Yoo2, Hee Jae Huh2, Nam Yong Lee2, Byung Woo Jhun3.
Abstract
We evaluated the efficacy of intermittent azithromycin and ethambutol therapy for noncavitary Mycobacterium avium complex pulmonary disease (MAC-PD). Twenty-nine (76%) of 38 patients achieved sputum culture conversion after 12 months of treatment, and sputum smear positivity was an independent factor for failure to achieve culture conversion (adjusted odds ratio, 26.7; 95% confidence interval, 2.1 to 339.9; P = 0.011). Intermittent azithromycin and ethambutol may be an optional treatment regimen for noncavitary MAC-PD.Entities:
Keywords: Mycobacterium avium complex; ethambutol; intermittent therapy; macrolide
Year: 2019 PMID: 31611366 PMCID: PMC7187621 DOI: 10.1128/AAC.01787-19
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191