| Literature DB >> 31607664 |
Sharmila Dorbala1, Sarah Cuddy2, Rodney H Falk3.
Abstract
Cardiac amyloidosis (CA) is one of the most rapidly progressive forms of heart disease, with a median survival from diagnosis, if untreated, ranging from <6 months for light chain amyloidosis to 3 to 5 years for transthyretin amyloidosis. Early diagnosis and accurate typing of CA are necessary for optimal management of these patients. Emerging novel disease modifying therapies increase the urgency to diagnose CA at an early stage and identify patients who may benefit from these life-saving therapies. The goal of this review is to provide a practical approach to echocardiography, cardiac magnetic resonance, and radionuclide imaging in patients with known or suspected CA.Entities:
Keywords: CMR; PET; Tc-99m−PYP; amyloid tracers; cardiac amyloidosis; cardiac magnetic resonance; echocardiography; imaging; multimodality; pyrophosphate; radionuclide imaging
Mesh:
Year: 2019 PMID: 31607664 PMCID: PMC7148180 DOI: 10.1016/j.jcmg.2019.07.015
Source DB: PubMed Journal: JACC Cardiovasc Imaging ISSN: 1876-7591