Literature DB >> 31606242

Susceptibility evolution to antibiotics of Enterobacter cloacae, Morganella morganii, Klebsiella aerogenes and Citrobacter freundii involved in urinary tract infections: an 11-year epidemiological surveillance study.

Gemma Jiménez-Guerra1, Jaime Borrego-Jiménez1, Blanca Gutiérrez-Soto2, Manuela Expósito-Ruiz3, José María Navarro-Marí1, José Gutiérrez-Fernández4.   

Abstract

INTRODUCTION: The objective of this study was to analyse the susceptibility to antibiotic of Citrobacter freundii, Klebsiella aerogenes, Enterobacter cloacae, Serratia marcescens, Providencia stuartii and Morganella morganii (CESPM group), detected in urine cultures.
METHODS: Between 2006 and 2016 we analyzed CESPM group Enterobacteria isolated from urine cultures from both primary health-care centers and Hospital Virgen de las Nieves (Granada). We studied the susceptibility to aminoglycosides, fosfomycin, nitrofurantoin, quinolones, piperacillin/tazobactam, cefepime, imipenem and trimethoprim/sulfamethoxazole following CLSI interpretation criteria.
RESULTS: A total of 736 isolates were studied: 30.57% E. cloacae, 23.50% M. morganii, 20.38% K. aerogenes, 10.32% C. freundii, 8.83% S. marcescens and 6.38% P. stuartii. A significant decrease in the antibiotic susceptibility was observed. Gentamicin, ciprofloxacin, imipenem and cefepime showed susceptibility over 80%.
CONCLUSIONS: E. cloacae, M. morganii and K. aerogenes were the most common isolates. Cefepime and imipenem are still a good empiric therapeutic alternative given its activity in vitro.
Copyright © 2019 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

Entities:  

Keywords:  AmpC β-lactamases; Enterobacteriaceae; Infección del tracto urinario; Urinary tract infections; β-lactamasas AmpC

Year:  2019        PMID: 31606242     DOI: 10.1016/j.eimc.2019.07.010

Source DB:  PubMed          Journal:  Enferm Infecc Microbiol Clin (Engl Ed)        ISSN: 2529-993X


  4 in total

1.  Draft Genome Sequence of Citrobacter freundii UFMG-H9, Isolated from Urine from a Healthy Bovine Heifer (Gyr Breed).

Authors:  Silvia Giannattasio-Ferraz; Laura Maskeri; André P Oliveira; Edel F Barbosa-Stancioli; Catherine Putonti
Journal:  Microbiol Resour Announc       Date:  2020-05-07

2.  Draft Genome Sequence of Enterobacter asburiae UFMG-H9, Isolated from Urine from a Healthy Bovine Heifer (Gyr Breed).

Authors:  Silvia Giannattasio-Ferraz; Laura Maskeri; André Penido Oliveira; Edel F Barbosa-Stancioli; Catherine Putonti
Journal:  Microbiol Resour Announc       Date:  2020-05-21

3.  High clinical impact of rapid susceptibility testing on CHROMID ESBL® medium directly from swabs.

Authors:  Álvaro Romo-Ibáñez; Elisabeth Calatrava-Hernández; Blanca Gutiérrez-Soto; Mercedes Pérez-Ruiz; José María Navarro-Marí; José Gutiérrez-Fernández
Journal:  Ann Transl Med       Date:  2020-05

4.  Clinical and drug resistance characteristics of Providencia stuartii infections in 76 patients.

Authors:  Jiachang Liu; Ruikai Wang; Ming Fang
Journal:  J Int Med Res       Date:  2020-10       Impact factor: 1.671

  4 in total

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