Literature DB >> 31605565

Insights into the labeling effect of Kidney Donor Performance Index reporting: The Australian experience.

Matthew P Sypek1,2,3, Peter Hughes2,3, Rhonda Holdsworth4, John Kanellis5, Stephen McDonald1,6,7, Philip D Clayton1,6,7.   

Abstract

In 2016, Australia began reporting the Kidney Donor Performance Index (KDPI) with all deceased donor kidney transplant offers despite this not being used in organ allocation rules, offering a unique opportunity to explore the "labeling effect" of KDPI reporting. We reviewed all kidneys retrieved for transplant in Australia from 2015 to 2018 and analyzed the association of KDPI reporting with organ nonutilization, number of offer declines, and donor/recipient age and longevity matching. Analyses were stratified by organ failure risk: higher risk (KDPI > 80%), standard risk (KDPI 20% to 79%), and lower risk (KDPI 0% to 20%). There was no significant difference in organ nonutilization post KDPI reporting either overall or for higher-risk kidneys. KDPI reporting was associated with an increase in offer declines for both higher-risk (incidence risk ratio 1.45, P = .007) and standard-risk (incidence risk ratio 1.22, P = .021) kidneys but not for lower-risk organs. There was a significant increase in recipient age and expected posttransplant survival score for higher-risk kidneys but no differences among other groups. We conclude that although KDPI reporting in Australia has been associated with an increased number of offer declines for higher-risk kidneys, this has not resulted in increased nonutilization and may have contributed to more appropriate use of these organs.
© 2019 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  clinical research; donors and donation: deceased; epidemiology; kidney transplantation; nephrology; organ procurement; organ procurement and allocation; practice; registry; registry analysis

Mesh:

Year:  2019        PMID: 31605565     DOI: 10.1111/ajt.15656

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  2 in total

1.  Beyond Graft Survivl: A National Cohort Study Quantifying the Impact of Increasing Kidney Donor Profile Index on Recipient Outcomes 1 Year Post-transplantation.

Authors:  Emma K Tully; Ian P Hayes; Peter D Hughes; Matthew P Sypek
Journal:  Transplant Direct       Date:  2022-04-21

2.  Successful Implementation of an Increased Viral Risk Donor Waiting List for Preconsented Kidney Transplant Candidates in Victoria, Australia.

Authors:  Darren Lee; Indra Gramnea; Nina Seng; Meaghan Bruns; Fiona Hudson; Rohit D'Costa; Leanne McEvoy; Joe Sasadeusz; Michael J O'Leary; Gopal Basu; Joshua Y Kausman; Rosemary Masterson; Kathy Paizis; John Kanellis; Peter D Hughes; David J Goodman; John B Whitlam
Journal:  Transplant Direct       Date:  2021-09-07
  2 in total

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