Literature DB >> 31605561

Outcomes of en bloc simultaneous liver-kidney transplantation compared to the traditional technique.

Tiffany C Lee1,2, Alexander R Cortez1,2, Al-Faraaz Kassam2, Mackenzie C Morris1,2, Leah K Winer1,2, Latifa S Silski2, Ralph C Quillin1,2, Madison C Cuffy2, Courtney R Jones3, Tayyab S Diwan2, Shimul A Shah1,2.   

Abstract

Simultaneous liver-kidney transplantation (SLKT) is indicated for patients with end-stage liver disease (ESLD) and concurrent renal insufficiency. En bloc SLKT is an alternative to traditional separate implantations, but studies comparing the two techniques are limited. The en bloc technique maintains renal outflow via donor infrahepatic vena cava and inflow via anastomosis of donor renal artery to donor splenic artery. Comparison of recipients of en bloc (n = 17) vs traditional (n = 17) SLKT between 2013 and 2017 was performed. Recipient demographics and comorbidities were similar. More recipients of traditional SLKT were dialysis dependent (82.4% vs 41.2%, P = .01) with lower baseline pretransplant eGFR (14 vs 18, P = .01). En bloc SLKT was associated with shorter kidney cold ischemia time (341 vs 533 minutes, P < .01) and operative time (374 vs 511 minutes, P < .01). Two en bloc patients underwent reoperation for kidney allograft inflow issues due to kinking and renal steal. Early kidney allograft dysfunction (23.5% in both groups), 1-year kidney graft survival (88.2% vs 82.4%, P = 1.0), and posttransplantation eGFR were similar between groups. In our experience, the en bloc SLKT technique is safe and feasible, with comparable outcomes to the traditional method.
© 2019 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  anatomy; clinical research/practice; hepatorenal syndrome; kidney (allograft) function/dysfunction; kidney transplantation/nephrology; liver transplantation/hepatology; recipient selection; surgical technique

Mesh:

Year:  2019        PMID: 31605561     DOI: 10.1111/ajt.15655

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  2 in total

1.  Advances in the Management of Renal Dysfunction in Patients With Cirrhosis.

Authors:  Nathalie A Pena Polanco; Paul Martin; Andres F Carrion
Journal:  Gastroenterol Hepatol (N Y)       Date:  2021-05

2.  Simultaneous right-sided nephrectomy with orthotopic liver and kidney transplantation-An alternative method for patients with autosomal dominant polycystic liver and kidney disease.

Authors:  Philipp Felgendreff; Hans-Michael Tautenhahn; Sascha Lux; Felix Dondorf; René Aschenbach; Falk Rauchfuss; Utz Settmacher
Journal:  Langenbecks Arch Surg       Date:  2021-05-26       Impact factor: 3.445

  2 in total

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