Literature DB >> 31605332

How Many Nodes Need to be Removed to Make Esophagectomy an Adequate Cancer Operation, and Does the Number Change When a Patient has Chemoradiotherapy Before Surgery?

Jonathan C Yeung1, Manjit S Bains2, Arianna Barbetta2, Tamar Nobel2, Steven R DeMeester3, Brian E Louie4, Mark B Orringer5, Linda W Martin6, Rishindra M Reddy5, Francisco Schlottmann2, Daniela Molena7.   

Abstract

INTRODUCTION AND
DESIGN: Node dissection during esophagectomy is an important aspect of esophageal cancer staging. Controversy remains as to how many nodes need to be resected in order to properly stage a patient and whether the removal of more nodes carries a stage-independent survival benefit. A review of the literature performed by a group of experts in the subject may help define a minimum accepted number of lymph nodes to be resected in both primary surgery and post-induction therapy scenarios. RESULTS AND
CONCLUSIONS: The existing evidence generally supports the goal of obtaining a minimum of 15 lymph nodes for pathological examination in both primary surgery and post-induction therapy scenarios.

Entities:  

Mesh:

Year:  2019        PMID: 31605332      PMCID: PMC7561013          DOI: 10.1245/s10434-019-07870-2

Source DB:  PubMed          Journal:  Ann Surg Oncol        ISSN: 1068-9265            Impact factor:   5.344


  5 in total

1.  Patterns and influence of nodal metastases after neoadjuvant chemoradiation and R0 resection in esophageal adenocarcinoma.

Authors:  Caitlin A Harrington; Rebecca A Carr; Meier Hsu; Kay See Tan; Smita Sihag; Prasad S Adusumilli; Manjit S Bains; Matthew J Bott; James M Isbell; Bernard J Park; Gaetano Rocco; Valerie W Rusch; David R Jones; Daniela Molena
Journal:  J Thorac Cardiovasc Surg       Date:  2022-03-01       Impact factor: 6.439

2.  Does the lymph node yield affect survival in patients with esophageal cancer receiving neoadjuvant therapy plus esophagectomy? A systematic review and updated meta-analysis.

Authors:  Donglai Chen; Yiming Mao; Yuhang Xue; Yonghua Sang; Desen Liu; Yongbing Chen
Journal:  EClinicalMedicine       Date:  2020-07-31

Review 3.  Evidence-based approach to the treatment of esophagogastric junction tumors.

Authors:  Francisco Schlottmann; María A Casas; Daniela Molena
Journal:  World J Clin Oncol       Date:  2022-03-24

4.  Learning Curve for Lymph Node Dissection Around the Recurrent Laryngeal Nerve in McKeown Minimally Invasive Esophagectomy.

Authors:  Zi-Yi Zhu; Rao-Jun Luo; Zheng-Fu He; Yong Xu; Shao-Hua Xu; Qiang Zhang
Journal:  Front Oncol       Date:  2021-05-20       Impact factor: 6.244

5.  Prognostic significance of the number of lymph nodes dissection in esophageal adenocarcinoma patients.

Authors:  Jingpu Wang; Yang Yang; Mohammed Shafiulla Shaik
Journal:  Transl Cancer Res       Date:  2020-05       Impact factor: 1.241

  5 in total

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