Literature DB >> 31605181

Risk Factors Associated with In-Hospital Mortality for Patients with Acute Abdomen After Cardiac Surgery.

I Djordjevic1, K Eghbalzadeh2, S Heinen3, G Schlachtenberger2, S Gerfer2, A Sabashnikov2, J Merkle2, C Weber2, E Kuhn2, M Zeriouh2, P Rahmanian2, N Mader2, O-J Liakopoulos2, T Wahlers2.   

Abstract

OBJECTIVES: Management of acute abdomen (AA) differs due to the heterogeneity of underlying pathophysiology. Complications of AA and its overall outcome after cardiac surgery are known to be associated with poor results. The aim of this retrospective analysis was to evaluate risk factors for AA in patients undergoing cardiac surgery.
METHODS: Between December 2011 and December 2014, a total of 131 patients with AA after cardiac surgery were identified and retrospectively analyzed using our institutional database. Statistical analysis of risk factors concerning in-hospital mortality of mentioned patient cohort was performed using IBM SPSS Statistics.
RESULTS: Overall in-hospital mortality was 54.2% (71/131). Analyzing in-hospital non-survivors (NS) versus in-hospital survivors (S) peripheral artery disease (28.2% vs. 11.7%; p = 0.03), the need for assist device therapy (33.8% vs. 16.7%; p = 0.03) and the requirement of hemodialysis (67.6% vs. 23.3%; p < 0.01) were significantly higher in NS. Furthermore, lactic acid values at onset of symptoms were shown to be significantly higher in NS (5.7 ± 5.7 mmol/L vs. 2.8 ± 2.9 mmol/L; p < 0.01). Assured diagnosis of mesenterial ischemia was strongly associated with worse outcome (odds ratio 10.800, 95% confidence interval 2.003-58.224; p = 0.006).
CONCLUSION: In conclusion, in critically ill patients after performed cardiac surgery peripheral vascular disease, need for supportive hemodynamic assist device systems and occurrence of renal failure are risk factors associated with worsen outcome. Additionally, rise of lactic acid could potentially be associated with onset of intestinal malperfusion and should be taken into account in therapeutic decisions preventing fatal mesenterial ischemia.

Entities:  

Year:  2020        PMID: 31605181     DOI: 10.1007/s00268-019-05227-0

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  43 in total

1.  Gastrointestinal complications after cardiac surgery.

Authors:  A T Yilmaz; M Arslan; U Demirkilç; E Ozal; E Kuralay; H Bingöl; B S Oz; H Tatar; O Y Oztürk
Journal:  Eur J Cardiothorac Surg       Date:  1996       Impact factor: 4.191

Review 2.  Acute mesenteric ischemia after cardio-pulmonary bypass surgery.

Authors:  Bassam Abboud; Ronald Daher; Joe Boujaoude
Journal:  World J Gastroenterol       Date:  2008-09-21       Impact factor: 5.742

Review 3.  Acute Kidney Injury in the Critically Ill Patient: A Current Review of the Literature.

Authors:  Andrea M Pakula; Ruby A Skinner
Journal:  J Intensive Care Med       Date:  2015-03-09       Impact factor: 3.510

4.  Hypoperfusion as a possible factor in the development of gastrointestinal complications after cardiac surgery.

Authors:  G L Moneta; G A Misbach; T D Ivey
Journal:  Am J Surg       Date:  1985-05       Impact factor: 2.565

Review 5.  Vasoplegia After Cardiovascular Procedures-Pathophysiology and Targeted Therapy.

Authors:  Shahzad Shaefi; Aaron Mittel; John Klick; Adam Evans; Natalia S Ivascu; Jacob Gutsche; John G T Augoustides
Journal:  J Cardiothorac Vasc Anesth       Date:  2017-10-27       Impact factor: 2.628

6.  Vasopressin as Therapy During Nonocclusive Mesenteric Ischemia.

Authors:  Hagen Bomberg; Heinrich V Groesdonk; Miriam Raffel; Peter Minko; Wolfram Schmied; Matthias Klingele; Hans-Joachim Schäfers
Journal:  Ann Thorac Surg       Date:  2016-05-10       Impact factor: 4.330

7.  Does off-pump CABG reduce gastrointestinal complications?

Authors:  Ilhan Sanisoglu; Mustafa Guden; Zehra Bayramoglu; Ertan Sagbas; Cengiz Dibekoglu; S Yavuz Sanisoglu; Belhhan Akpinar
Journal:  Ann Thorac Surg       Date:  2004-02       Impact factor: 4.330

Review 8.  Is it possible to predict the risk of ischaemic bowel after cardiac surgery?

Authors:  Kok Hooi Yap; Kim Chai Chua; See Lim Lim; Yoong Kong Sin
Journal:  Interact Cardiovasc Thorac Surg       Date:  2014-06-04

9.  Postoperative abdominal complications in cardiopulmonary bypass patients: a case-controlled study.

Authors:  M J Ott; T G Buchman; W A Baumgartner
Journal:  Ann Thorac Surg       Date:  1995-05       Impact factor: 4.330

10.  Intestinal ischemia after cardiac surgery: analysis of a large registry.

Authors:  Johan Nilsson; Erika Hansson; Bodil Andersson
Journal:  J Cardiothorac Surg       Date:  2013-06-18       Impact factor: 1.637

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