Literature DB >> 31604810

Another Tool in the Fight Against Phosphate Toxicity: Where Will It Fit and What Does It Tell Us about Phosphate Homeostasis?

Eleanor Lederer1.   

Abstract

Entities:  

Keywords:  kidney phosphate handling; parathyroid hormone; phosphate transporter; transport inhibitor

Mesh：

Substances：

Year:  2019        PMID： 31604810      PMCID： PMC6830797          DOI： 10.1681/ASN.2019090924

Source DB:  PubMed          Journal:  J Am Soc Nephrol        ISSN： 1046-6673            Impact factor:   10.121


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  4 in total

1.  Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1).

Authors:  Kevin J Filipski; Matthew F Sammons; Samit K Bhattacharya; Jane Panteleev; Janice A Brown; Paula M Loria; Markus Boehm; Aaron C Smith; Andre Shavnya; Edward L Conn; Kun Song; Yan Weng; Carie Facemire; Harald Jüppner; Valerie Clerin
Journal:  ACS Med Chem Lett       Date:  2018-04-12       Impact factor: 4.345

2.  Impaired Phosphate Tolerance Revealed With an Acute Oral Challenge.

Authors:  Mandy E Turner; Christine A White; Wilma M Hopman; Emilie C Ward; Paul S Jeronimo; Michael A Adams; Rachel M Holden
Journal:  J Bone Miner Res       Date:  2017-10-19       Impact factor: 6.741

3.  Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function.

Authors:  Linto Thomas; Jianxiang Xue; Sathish Kumar Murali; Robert A Fenton; Jessica A Dominguez Rieg; Timo Rieg
Journal:  J Am Soc Nephrol       Date:  2019-08-13       Impact factor: 10.121

4.  Parathyroid hormone (PTH) decreases sodium-phosphate cotransporter type IIa (NpT2a) mRNA stability.

Authors:  Rebecca D Murray; Kristine Holthouser; Barbara J Clark; Sarah A Salyer; Michelle T Barati; Syed J Khundmiri; Eleanor D Lederer
Journal:  Am J Physiol Renal Physiol       Date:  2013-01-23
  4 in total
  1 in total

1.  PF-06869206 is a selective inhibitor of renal Pi transport: evidence from in vitro and in vivo studies.

Authors:  Linto Thomas; Jianxiang Xue; Viktor N Tomilin; Oleh M Pochynyuk; Jessica A Dominguez Rieg; Timo Rieg
Journal:  Am J Physiol Renal Physiol       Date:  2020-08-03
  1 in total

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