Scott E Hadland1, Louisa Degenhardt2. 1. Grayken Center for Addiction, Department of Pediatrics, Boston Medical Center, Boston, MA 02118, USA; Department of Pediatrics, Division of General Pediatrics, Boston University School of Medicine, Boston, MA, USA. Electronic address: scott.hadland@bmc.org. 2. National Drug and Alcohol Research Centre, UNSW Sydney, Sydney, NSW, Australia.