| Literature DB >> 31602895 |
Guang-Zhao Zhu1, Xiao-Chen Han2, Han-Zhou Wang3, Yu-Zheng Yang3, Yang Gao4, Hai-Long Wang4.
Abstract
To evaluate the effect of Tripterygium Glycosides Tablets extract in the treatment of rheumatoid arthritis( RA). Clinical trials of treating rheumatoid arthritis with Tripterygium Glycosides Tablets published by Meta-analysis were retrieved from EMbase,PubMed,Clinical Trials,Web of Science,Cochrane Library,CNKI,Wanfang,VIP,CBM and Chi CTR,and comprehensively analyzed. A total of 3 studies were enrolled,the modified Sharp score( m TSS),tender join joint erosions( JE) and joint space narrowing( JSN) of Tripterygium Glycosides Tablets group were significant superior to those of control group,including positive drugs methotrexate( MTX) and salazopyridine( SSZ)( P<0. 01). Tripterygium Glycosides Tablets had an effect in treating RA. Due to the small sample size,this study shall be verified with high-quality,large-sample-size double-blinded RCTs.Entities:
Keywords: Meta-analysis; Tripterygium Glycosides Tablets; radiological progression; rheumatoid arthritis
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Year: 2019 PMID: 31602895 DOI: 10.19540/j.cnki.cjcmm.20190305.004
Source DB: PubMed Journal: Zhongguo Zhong Yao Za Zhi ISSN: 1001-5302