| Literature DB >> 31602444 |
Shuhua Cao1, Jiangli Fan2, Wen Sun2, Fahui Li3, Kaoxue Li4, Xishi Tai4, Xiaojun Peng2.
Abstract
A bimetallic complex, containing Mn(ii) and Cu(ii) moieties, was synthesized for chemodynamic therapy (CDT) of cancer. The complex was capable of generating a hydroxyl radical (˙OH) via a Fenton-like reaction involving a Mn complex, and simultaneously depleting glutathione via a Cu complex induced oxidative reaction, thereby enhancing the efficiency of CDT.Entities:
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Year: 2019 PMID: 31602444 DOI: 10.1039/c9cc06040e
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222