Literature DB >> 3160110

Inhibition of interferon-gamma may suppress allograft reactivity by T lymphocytes in vitro and in vivo.

S Landolfo, F Cofano, M Giovarelli, M Prat, G Cavallo, G Forni.   

Abstract

The addition to mixed-leukocyte reactions of monoclonal antibodies to interferon-gamma abrogated alloantigen recognition and induction of cytotoxic T lymphocytes by inducing early and highly effective suppressor T lymphocytes. This inhibitory activity was not confined to in vitro models, since daily injection of the antibodies into CBA/J mice blocked the usual rejection of allogenic tumor cells.

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Year:  1985        PMID： 3160110     DOI： 10.1126/science.3160110

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  20 in total

1.  Modulation of human interferon-gamma biosynthesis by antisense oligodeoxynucleotides.

Authors:  C M Boeve; M De Ley
Journal:  Mol Biotechnol       Date:  2000-02       Impact factor: 2.695

2.  The in vitro effects of interleukin-12 upon tumor-infiltrating lymphocytes derived from renal cell carcinoma.

Authors:  G G Steger; M F Gnant; M P Djavanmard; R M Mader; R Jakesz; W Pierce; J B deKernion; R Figlin; A Belldegrun
Journal:  J Cancer Res Clin Oncol       Date:  1997       Impact factor: 4.553

Review 3.  Pharmacodynamic monitoring of cyclosporin.

Authors:  W M Awni
Journal:  Clin Pharmacokinet       Date:  1992-12       Impact factor: 6.447

4.  The effect of a single whole-blood transfusion on cytokine secretion.

Authors:  Y Kalechman; U Gafter; D Sobelman; B Sredni
Journal:  J Clin Immunol       Date:  1990-03       Impact factor: 8.317

5.  Transforming growth factor beta decreases the immunogenicity of rat islet xenografts (rat to mouse) and prevents rejection in association with treatment of the recipient with a monoclonal antibody to interferon gamma.

Authors:  J C Carel; R D Schreiber; L Falqui; P E Lacy
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

Review 6.  Current thoughts on the pathogenesis of graft versus host disease.

Authors:  A L Appleton; L Sviland
Journal:  J Clin Pathol       Date:  1993-09       Impact factor: 3.411

7.  Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors.

Authors:  S Chouaib; J Chehimi; L Bani; N Genetet; T Tursz; F Gay; G Trinchieri; F Mami-Chouaib
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205

8.  Antibodies to IFN-gamma prevent immunologically mediated intestinal damage in murine graft-versus-host reaction.

Authors:  A M Mowat
Journal:  Immunology       Date:  1989-09       Impact factor: 7.397

9.  Effects of cytokines on in vitro growth of tumor-infiltrating lymphocytes obtained from human primary and metastatic liver tumors.

Authors:  Y Shimizu; S Iwatsuki; R B Herberman; T L Whiteside
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

10.  Inhibition of interferon-gamma by an interferon-gamma receptor immunoadhesin.

Authors:  M Haak-Frendscho; S A Marsters; S M Chamow; D H Peers; N J Simpson; A Ashkenazi
Journal:  Immunology       Date:  1993-08       Impact factor: 7.397
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