| Literature DB >> 31599643 |
Peng Wang1, Chao Huang2, Zhaowei Meng1, Wenjuan Zhang3, Yongle Li3, Xuefang Yu3, Xin Du3, Ming Liu4, Jinhong Sun5, Qing Zhang5, Ying Gao5, Kun Song5, Xing Wang5, Yaguang Fan6, Li Zhao7.
Abstract
Aim: We aimed to explore gender impacts on the associations between red blood cell distribution width (RDW) and thyroid function in the Chinese population. Methods/results: Gender impacts on the associations between RDW and thyroid function in 8424 males and 5198 females were investigated. RDW was found significantly lower in males than in females. An increasing trend of RDW along with aging was demonstrated in males. For females, an obvious decrease was shown during menopause period. From binary logistic regression, RDW displayed negative relationship with hypothyroidism in both genders as a single factor. However, if RDW was analyzed as a categorical variable (in RDW width quartiles) and as a continuous variable in models with covariates, all the odds ratios were negative, except for a weak-negative relationship with hypothyroidism in women in a continuous RDW model.Entities:
Keywords: RDW; TSH; anisocytosis; binary logistic regression; gender; hyperthyroidism; hypothyroidism; odds ratio; quartiles; red blood cell distribution width; thyroid dysfunction; thyroid stimulating hormone
Mesh：
Year: 2019 PMID： 31599643 DOI： 10.2217/bmm-2018-0476
Source DB: PubMed Journal: Biomark Med ISSN： 1752-0363 Impact factor: 2.851