Gassan Moady1, Amitai Bickel2,3, Alexander Shturman1,3, Muhammad Khader1, Shaul Atar1,3. 1. Department of Cardiology, Galilee Medical Center, Nahariya, Israel. 2. Department of Surgery, Galilee Medical Center, Nahariya, Israel. 3. Azrieli Faculty of Medicine, Bar-Ilan University of the Galilee, Safed, Israel.
Abstract
BACKGROUND: Pneumatic sleeves (PS) are often used during laparoscopic surgery and for prevention of deep vein thrombosis in patients who cannot receive anticoagulation treatment. There is very little information on the hemodynamic changes induced by PS and their effect on brain natriuretic peptide (BNP) in patients with severely reduced left ventricular ejection function (LVEF). OBJECTIVES: To determine the safety and hemodynamic changes induced by PS and their effects on brain natriuretic peptide (BNP). METHODS: This study comprised 14 patients classified as New York Heart Association (NYHA) II-III with severely reduced LVEF (< 40%). We activated the PS using two inflation pressures (50 or 80 mmHg, 7 patients in each group) at two cycles per minute for one hour. We measured echocardiography, hemodynamic parameters, and BNP levels in each patient prior to, during, and after the PS operation. RESULTS: The baseline LVEF did not change throughout the activation of PS (31 ± 10% vs. 33 ± 9%, P = 0.673). Following PS activation there was no significant difference in systolic or diastolic blood pressure, the pulse measurements, or central venous pressure. BNP levels did not change after PS activation (P = 0.074). CONCLUSIONS: The use of PS, with either low or high inflation pressures, is safe and has no detrimental effects on hemodynamic parameters or BNP levels in patients with severely reduced LVEF following clinical stabilization and optimal medical therapy.
BACKGROUND: Pneumatic sleeves (PS) are often used during laparoscopic surgery and for prevention of deep vein thrombosis in patients who cannot receive anticoagulation treatment. There is very little information on the hemodynamic changes induced by PS and their effect on brain natriuretic peptide (BNP) in patients with severely reduced left ventricular ejection function (LVEF). OBJECTIVES: To determine the safety and hemodynamic changes induced by PS and their effects on brain natriuretic peptide (BNP). METHODS: This study comprised 14 patients classified as New York Heart Association (NYHA) II-III with severely reduced LVEF (< 40%). We activated the PS using two inflation pressures (50 or 80 mmHg, 7 patients in each group) at two cycles per minute for one hour. We measured echocardiography, hemodynamic parameters, and BNP levels in each patient prior to, during, and after the PS operation. RESULTS: The baseline LVEF did not change throughout the activation of PS (31 ± 10% vs. 33 ± 9%, P = 0.673). Following PS activation there was no significant difference in systolic or diastolic blood pressure, the pulse measurements, or central venous pressure. BNP levels did not change after PS activation (P = 0.074). CONCLUSIONS: The use of PS, with either low or high inflation pressures, is safe and has no detrimental effects on hemodynamic parameters or BNP levels in patients with severely reduced LVEF following clinical stabilization and optimal medical therapy.
Authors: Hasan M Al-Dorzi; Abdulaziz Al-Dawood; Fahad M Al-Hameed; Karen E A Burns; Sangeeta Mehta; Jesna Jose; Sami Alsolamy; Sheryl Ann I Abdukahil; Lara Y Afesh; Mohammed S Alshahrani; Yasser Mandourah; Ghaleb A Almekhlafi; Mohammed Almaani; Ali Al Bshabshe; Simon Finfer; Zia Arshad; Imran Khalid; Yatin Mehta; Atul Gaur; Hassan Hawa; Hergen Buscher; Hani Lababidi; Abdulsalam Al Aithan; Yaseen M Arabi Journal: Sci Rep Date: 2022-05-20 Impact factor: 4.996