Literature DB >> 31599283

Development of 4-oxime-1,8-naphthalimide as a bioorthogonal turn-on probe for fluorogenic protein labeling.

Yulin Tian1, Xiang Li1, Dali Yin1.   

Abstract

4-Oxime-1,8-naphthalimide was reported as a novel bioorthogonal turn-on probe based on 1,3-dipolar cycloaddition reactions between in situ generated nitrile oxide and alkenes/alkynes. The resulting isoxazole products displayed dramatically strong fluorescence enhancement upon photoirradiation through isoxazole-oxazole photoisomerization. This new methodology was successfully applied for in situ fluorogenic protein labeling.

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Year:  2019        PMID： 31599283     DOI： 10.1039/c9cc06769h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  A Polyamine-Based Dinitro-Naphthalimide Conjugate as Substrates for Polyamine Transporters Preferentially Accumulates in Cancer Cells and Minimizes Side Effects in vitro and in vivo.

Authors:  Jing Ma; Yingguang Li; Linrong Li; Kexin Yue; Hanfang Liu; Jiajia Wang; Zhuoqing Xi; Man Shi; Sihan Zhao; Qi Ma; Sitong Liu; Shudi Guo; Jianing Liu; Lili Hou; Chaojie Wang; Peng George Wang; Zhiyong Tian; Songqiang Xie
Journal:  Front Chem       Date:  2020-04-09       Impact factor: 5.221

2.  A Dansyl Amide N-Oxide Fluorogenic Probe Based on a Bioorthogonal Decaging Reaction.

Authors:  Hong Yang; Yongcheng Wang; Xiang Li; Yu Teng; Yulin Tian
Journal:  ChemistryOpen       Date:  2021-10       Impact factor: 2.630

3.  A novel dual-capability naphthalimide-based fluorescent probe for Fe3+ ion detection and lysosomal tracking in living cells.

Authors:  Xinran Li; Wenwu Qin
Journal:  RSC Adv       Date:  2022-08-26       Impact factor: 4.036
  3 in total

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