Quintí Foguet-Boreu1,2, Anna Guàrdia Sancho3,4, Jose Manuel Santos Lopez1, Pere Roura Poch1,5, Joan Palmarola Ginesta1, Anna Maria Puig-Ribera3, Jordina Muñoz Pradós1. 1. Department of Psychiatry, Vic University Hospital, Vic, Spain. 2. Faculty of Health Sciences and Welfare, University of Vic - Central University of Catalonia (UVic-UCC), Vic, Spain. 3. Sport and Physical Activity Research Group, Centre for Health and Social Care Research, Department of Physical Activity and Sports Sciences, University of Vic - Central University of Catalonia, Vic, Spain. 4. Osonament - Osona Psychopedagogical Medical Center, Vic, Spain. 5. School of Medicine, University of Vic - Central University of Catalonia (UVic-UCC), Vic, Spain.
Abstract
Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationship between cognition and vascular burden in patients with SMD. Methods: Sixty SMD patients (61% men, mean age: 46) attending a psychosocial rehabilitation centre were included. We evaluated sociodemographic, clinical, laboratory, quality of life and functionality characteristics. And we analysed the association between cognitive performance and vascular burden. Results: SMD diagnoses were: 41.7% schizophrenia, 20.0% bipolar, 5.0% schizoaffective, 21.7% depressive and 11.7% other. Cognitive impairment was present in 55% of the cases. The average vascular burden was 3.2. Patients with cognitive impairment have a significantly higher vascular burden than patients without cognitive impairment (p < 0.05). The speed of processing had a moderate correlation with vascular burden (r = -0.457, p = 0.001).Conclusions: Patients with cognitive impairment had a significantly higher vascular burden than patients without cognitive impairment. There are two practical clinical implications: CVR should be evaluated in all SMD patients; and psychoeducation programmes for CVR should be performed and adapted to the cognitive deficits.
Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationship between cognition and vascular burden in patients with SMD. Methods: Sixty SMD patients (61% men, mean age: 46) attending a psychosocial rehabilitation centre were included. We evaluated sociodemographic, clinical, laboratory, quality of life and functionality characteristics. And we analysed the association between cognitive performance and vascular burden. Results: SMD diagnoses were: 41.7% schizophrenia, 20.0% bipolar, 5.0% schizoaffective, 21.7% depressive and 11.7% other. Cognitive impairment was present in 55% of the cases. The average vascular burden was 3.2. Patients with cognitive impairment have a significantly higher vascular burden than patients without cognitive impairment (p < 0.05). The speed of processing had a moderate correlation with vascular burden (r = -0.457, p = 0.001).Conclusions: Patients with cognitive impairment had a significantly higher vascular burden than patients without cognitive impairment. There are two practical clinical implications: CVR should be evaluated in all SMD patients; and psychoeducation programmes for CVR should be performed and adapted to the cognitive deficits.
Authors: Lusi Zhang; Scot Kristian Hill; Bin Guo; Baolin Wu; Ney Alliey-Rodriguez; Seenae Eum; Paulo Lizano; Elena I Ivleva; James L Reilly; Richard S E Keefe; Sarah K Keedy; Carol A Tamminga; Godfrey D Pearlson; Brett A Clementz; Matcheri S Keshavan; Elliot S Gershon; John A Sweeney; Jeffrey R Bishop Journal: Prog Neuropsychopharmacol Biol Psychiatry Date: 2021-10-29 Impact factor: 5.067
Authors: Mario Luciano; Gaia Sampogna; Mario Amore; Ileana Andriola; Pietro Calcagno; Claudia Carmassi; Valeria Del Vecchio; Liliana Dell'Osso; Giorgio Di Lorenzo; Barbara Gelao; Vincenzo Giallonardo; Alessandro Rossi; Rodolfo Rossi; Alberto Siracusano; Andrea Fiorillo Journal: Eur Psychiatry Date: 2021-11-23 Impact factor: 5.361