Objectives: This study aims to evaluate the prevalence of depressive symptoms among systemic sclerosis (SSc) patients using the Major Depression Inventory (MDI), identify possible risk factors, and analyze the current standard of care to raise awareness and improve clinical care for SSc patients. Patients and methods: The study included 94 SSc patients (12 males, 82 females; mean age 58.3±13.6 years; range, 28 to 83 years) who completed the MDI, Short Form 36 Health Survey, Scleroderma Health Assessment Questionnaire, Brief Fatigue Inventory and Physical Activity Questionnaire. Clinical parameters were assessed according to standardized procedures. Discharge letters were analyzed for evaluation of depressive symptoms. Results: The prevalence of depressive symptoms was 22.3%. It correlated with female sex (p=0.047), underweight (p=0.002), fatigue (p<0.001), decreased quality of life (p<0.001) and less physical activity (p=0.048). The latter three were confirmed as independent risk factors in a multivariable regression analysis. The analysis of the current standard of care revealed no assessment of depressive symptoms in the majority of patients (89.4%), including 19 with depressive symptoms according to the MDI score. Conclusion: This study confirms the high prevalence of depressive symptoms in SSc patients. There is an unmet need of regular assessment of mental health during SSc consultations. Fatigue, decreased quality of life and reduced physical activity were ascertained as independent risk factors, while special attention should also be paid to weight loss and underweight.
Objectives: This study aims to evaluate the prevalence of depressive symptoms among systemic sclerosis (SSc) patients using the Major Depression Inventory (MDI), identify possible risk factors, and analyze the current standard of care to raise awareness and improve clinical care for SScpatients. Patients and methods: The study included 94 SScpatients (12 males, 82 females; mean age 58.3±13.6 years; range, 28 to 83 years) who completed the MDI, Short Form 36 Health Survey, Scleroderma Health Assessment Questionnaire, Brief Fatigue Inventory and Physical Activity Questionnaire. Clinical parameters were assessed according to standardized procedures. Discharge letters were analyzed for evaluation of depressive symptoms. Results: The prevalence of depressive symptoms was 22.3%. It correlated with female sex (p=0.047), underweight (p=0.002), fatigue (p<0.001), decreased quality of life (p<0.001) and less physical activity (p=0.048). The latter three were confirmed as independent risk factors in a multivariable regression analysis. The analysis of the current standard of care revealed no assessment of depressive symptoms in the majority of patients (89.4%), including 19 with depressive symptoms according to the MDI score. Conclusion: This study confirms the high prevalence of depressive symptoms in SScpatients. There is an unmet need of regular assessment of mental health during SSc consultations. Fatigue, decreased quality of life and reduced physical activity were ascertained as independent risk factors, while special attention should also be paid to weight loss and underweight.
Authors: Adrienne O'Neil; Aaron J Fisher; Katherine J Kibbey; Felice N Jacka; Mark A Kotowicz; Lana J Williams; Amanda L Stuart; Michael Berk; Paul A Lewandowski; Craig B Taylor; Julie A Pasco Journal: J Affect Disord Date: 2016-02-16 Impact factor: 4.839
Authors: Lisa M Benrud-Larson; Jennifer A Haythornthwaite; Leslie J Heinberg; Christy Boling; Jeffrey Reed; Barbara White; Fredrick M Wigley Journal: Pain Date: 2002-02 Impact factor: 6.961
Authors: Linda Kwakkenbos; Wim G J M van Lankveld; Madelon C Vonk; Eni S Becker; Frank H J van den Hoogen; Cornelia H M van den Ende Journal: J Psychosom Res Date: 2012-01-16 Impact factor: 3.006
Authors: Chingching Foocharoen; Alan Tyndall; Eric Hachulla; Edoardo Rosato; Yannick Allanore; Dominique Farge-Bancel; Paola Caramaschi; Paolo Airó; Starovojtova M Nikolaevna; José António Pereira da Silva; Bojana Stamenkovic; Gabriela Riemekasten; Simona Rednic; Jean Sibilia; Piotr Wiland; Ingo Tarner; Vanessa Smith; Anna T Onken; Walid Ahmed Abdel Atty Mohamed; Oliver Distler; Jadranka Morović-Vergles; Andrea Himsel; Paloma Garcia de la Peña Lefebvre; Thomas Hügle; Ulrich A Walker Journal: Arthritis Res Ther Date: 2012-02-20 Impact factor: 5.156