Literature DB >> 31593731

Legume lectins: Potential use as a diagnostics and therapeutics against the cancer.

Ajay Kumar Gautam1, Divakar Sharma2, Juhi Sharma3, Khem Chand Saini4.   

Abstract

Legume lectins are carbohydrate-binding protein and widely distributed in a variety of species of leguminous plants and have drawn increased attention toward cancer. Nowadays, the lectins have been studied for the screening of potential biomarkers which increased its importance in cancer research. Few plant lectins have been shown to destroy cancer cells, suggesting that lectins may have biological potential in cancer treatments. In this review, we present a focused outline of legume lectins in descriptive their complex anti-cancer mechanisms on the bases of their properties of recognition and interacting specifically with carbohydrates binding sites. Existing reports suggested the binding of lectins to cancerous cells with their cell surface markers speculated by histochemistry in vitro and in vivo. In this review, we illuminate the use of legume lectins as a natural source for diagnostics and therapeutics purpose against cancer.
Copyright © 2019 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Biomarkers; Cancer; Cancer cell lines; Legume lectins; Therapeutics

Mesh:

Substances:

Year:  2019        PMID: 31593731     DOI: 10.1016/j.ijbiomac.2019.09.119

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN: 0141-8130            Impact factor:   6.953


  7 in total

1.  Cloning, Characterization, Expression Analysis, and Agglutination Studies of Novel Gene Encoding β-D-Galactose, N-Acetyl-D-Glucosamine and Lactose-Binding Lectin from Rice Bean (Vigna umbellata).

Authors:  Ankur Tripathi; Vipin Hallan; Rajan Katoch
Journal:  Mol Biotechnol       Date:  2021-10-05       Impact factor: 2.695

2.  Appraising diet-disease associations to be used in risk assessment, including an insight in nutritional epidemiology.

Authors:  Vânia Mendes; Aikaterini Niforou; Androniki Naska
Journal:  EFSA J       Date:  2022-05-25

Review 3.  Lectin Protein as a Promising Component to Functionalize Micelles, Liposomes and Lipid NPs against Coronavirus.

Authors:  Mehran Alavi; Kofi Asare-Addo; Ali Nokhodchi
Journal:  Biomedicines       Date:  2020-12-07

4.  Widening the Perspectives for Legume Consumption: The Case of Bioactive Non-nutrients.

Authors:  Rafaela Geraldo; Carla S Santos; Elisabete Pinto; Marta W Vasconcelos
Journal:  Front Plant Sci       Date:  2022-02-10       Impact factor: 5.753

Review 5.  Research advances and prospects of legume lectins.

Authors:  Rajan Katoch; Ankur Tripathi
Journal:  J Biosci       Date:  2021       Impact factor: 1.826

6.  Inhibition of Carrageenan-Induced Acute Inflammation in Mice by the Microgramma vacciniifolia Frond Lectin (MvFL).

Authors:  Leydianne Leite de Siqueira Patriota; Dalila de Brito Marques Ramos; Mariana Gama E Silva; Angela Caroline Lima Amorim Dos Santos; Yasmym Araújo Silva; Patrícia Maria Guedes Paiva; Emmanuel Viana Pontual; Lidiane Pereira de Albuquerque; Rosemairy Luciane Mendes; Thiago Henrique Napoleão
Journal:  Polymers (Basel)       Date:  2022-04-15       Impact factor: 4.967

Review 7.  Is There Such a Thing as "Anti-Nutrients"? A Narrative Review of Perceived Problematic Plant Compounds.

Authors:  Weston Petroski; Deanna M Minich
Journal:  Nutrients       Date:  2020-09-24       Impact factor: 5.717

  7 in total

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