Literature DB >> 31593645

Ionic liquids: green and tailor-made solvents in drug delivery.

Weizi Huang1, Xiying Wu2, Jianping Qi3, Quangang Zhu2, Wei Wu3, Yi Lu4, Zhongjian Chen5.   

Abstract

Beyond their traditional use as green solvents, new applications have become available for ionic liquids (ILs) in drug delivery. Their flexible tunability enables task-specific optimization of ILs at molecular level. Thus, ILs have been exploited to improve the solubility and permeability of drugs and relieve the polymorphic problems associated with crystalline active pharmaceutical ingredients (APIs). Controlled preparation of drug nanocarriers are also achieved by using ILs either as media or as functional agents. Here, we highlight the importance and advantages of ILs in pharmaceutics and look towards the future of IL-based drug delivery.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Year:  2019        PMID： 31593645     DOI： 10.1016/j.drudis.2019.09.018

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  16 in total

1.  Docusate-Based Ionic Liquids of Anthelmintic Benzimidazoles Show Improved Pharmaceutical Processability, Lipid Solubility, and in Vitro Activity against Cryptococcus neoformans.

Authors:  Yogesh Sutar; Sophie R Fulton; Sagarkumar Paul; Sophie Altamirano; Susmit Mhatre; Hiwa Saeed; Pratikkumar Patel; Sudipta Mallick; Roopal Bhat; Vandana B Patravale; Harsh Chauhan; Kirsten Nielsen; Abhijit A Date
Journal:  ACS Infect Dis       Date:  2021-09-01       Impact factor: 5.084

Review 2.  Amphiphilic Ionic Liquids Capable to Formulate Organized Systems in an Aqueous Solution, Designed by a Combination of Traditional Surfactants and Commercial Drugs.

Authors:  Nahir Dib; Juana J Silber; N Mariano Correa; R Dario Falcone
Journal:  Pharm Res       Date:  2022-07-19       Impact factor: 4.580

Review 3.  Ionic Liquids: Emerging Antimicrobial Agents.

Authors:  Zhezheng Fang; Xianzi Zheng; Lu Li; Jianping Qi; Wei Wu; Yi Lu
Journal:  Pharm Res       Date:  2022-07-25       Impact factor: 4.580

Review 4.  Recent Developments in Ionic Liquid-Assisted Topical and Transdermal Drug Delivery.

Authors:  Md Korban Ali; Rahman Md Moshikur; Masahiro Goto; Muhammad Moniruzzaman
Journal:  Pharm Res       Date:  2022-07-01       Impact factor: 4.580

5.  Converting Tretinoin into Ionic Liquids for Improving Aqueous Solubility and Permeability across Skin.

Authors:  Xiying Wu; Jingjing Xuan; Qin Yu; Wei Wu; Yi Lu; Quangang Zhu; Zhongjian Chen; Jianping Qi
Journal:  Pharm Res       Date:  2022-03-29       Impact factor: 4.580

6.  Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure.

Authors:  Erin Tay; Tri-Hung Nguyen; Leigh Ford; Hywel D Williams; Hassan Benameur; Peter J Scammells; Christopher J H Porter
Journal:  Pharmaceutics       Date:  2019-12-22       Impact factor: 6.321

Review 7.  A Review on Ionic Liquids-Based Membranes for Middle and High Temperature Polymer Electrolyte Membrane Fuel Cells (PEM FCs).

Authors:  Mohammad Ebrahimi; Wojciech Kujawski; Kateryna Fatyeyeva; Joanna Kujawa
Journal:  Int J Mol Sci       Date:  2021-05-21       Impact factor: 5.923

Review 8.  Roles of Lipids in the Permeability Barriers of Skin and Oral Mucosa.

Authors:  Philip W Wertz
Journal:  Int J Mol Sci       Date:  2021-05-15       Impact factor: 5.923

Review 9.  Advanced Materials in Cultural Heritage Conservation.

Authors:  Michele Baglioni; Giovanna Poggi; David Chelazzi; Piero Baglioni
Journal:  Molecules       Date:  2021-06-29       Impact factor: 4.411

Review 10.  Application of Ionic Liquids for Chemical Demulsification: A Review.

Authors:  Nahid Hassanshahi; Guangji Hu; Jianbing Li
Journal:  Molecules       Date:  2020-10-23       Impact factor: 4.411
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