Literature DB >> 31593459

Constituents from the Leaves of Tetraena mongolica and Their Protective Activity in HEK 293t Cells Damaged by CdCl2.

Zhi-Gang Wu1,2, Wei Wei1, Hai-Yan Xu1, Lin-Lin Zheng1,2, Chao-Mei Ma1, Ying-Chun Wang1.   

Abstract

Tetraena mongolica Maxim, a relict originating from the Tertiary Period, is an endemic species of Zygophyllaceae in China. Three new monoterpenoids (1-3), two new phenols (4, 5) with unusual O-sulfoglucosyl groups, a new flavonoid (6), and nine known compounds were isolated from the leaves of T. mongolica. The structures of these compounds were determined by interpretation of NMR, MS, and ECD data. Some of the isolated compounds showed protective effects on HEK 293t cells damaged by CdCl2, with IC50 values being 55.7 and 80.3 μM for compounds 7 and 8, respectively, at the time point of 48 h after treatment.

Entities:  

Year:  2019        PMID: 31593459     DOI: 10.1021/acs.jnatprod.9b00212

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  2 in total

1.  Identification of Genic SSRs Provide a Perspective for Studying Environmental Adaptation in the Endemic Shrub Tetraena mongolica.

Authors:  Zhenhua Dang; Lei Huang; Yuanyuan Jia; Peter J Lockhart; Yang Fong; Yunyun Tian
Journal:  Genes (Basel)       Date:  2020-03-18       Impact factor: 4.096

2.  Population genetic structure and gene flow of rare and endangered Tetraena mongolica Maxim. revealed by reduced representation sequencing.

Authors:  Jin Cheng; Huixia Kao; Shubin Dong
Journal:  BMC Plant Biol       Date:  2020-08-26       Impact factor: 4.215

  2 in total

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