S Kabashi1, V Vindenes2, E A Bryun3, E A Koshkina4, A V Nadezhdin3, E J Tetenova4, A J Kolgashkin4, A E Petukhov5, S N Perekhodov6, E N Davydova6, D Gamboa7, T Hilberg8, A Lerdal9, G Nordby7, C Zhang10, S T Bogstrand11. 1. Department of Forensic Sciences, Oslo University Hospital, Nydalen, Oslo, Norway; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway. 2. Department of Forensic Sciences, Oslo University Hospital, Nydalen, Oslo, Norway; Norwegian Centre for Addiction Research, University of Oslo, Blindern, Oslo, Norway. 3. Moscow Research and Practical Centre on Addictions of Moscow Department of Public Health, Moscow, Russia; Russian Medical Academy of Continuous Professional Education, Moscow, Russia. 4. Moscow Research and Practical Centre on Addictions of Moscow Department of Public Health, Moscow, Russia. 5. Moscow Research and Practical Centre on Addictions of Moscow Department of Public Health, Moscow, Russia; Sechenov First Moscow State Medical University, Moscow, Russia. 6. Demikhov Moscow Clinical Hospital, Moscow, Russia. 7. Medical Department, Lovisenberg Diaconal Hospital, Oslo, Norway. 8. Fürst Medical Laboratory, Oslo, Norway. 9. Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway; Department of Interdisciplinary Health Sciences, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway. 10. Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. 11. Department of Forensic Sciences, Oslo University Hospital, Nydalen, Oslo, Norway; Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway. Electronic address: stig.tore.bogstrand@ous-hf.no.
Abstract
BACKGROUND: The aim was to estimate the prevalence of harmful alcohol use in relation to socio-demographic characteristics among acutely ill medical patients, and examine identification measures of alcohol use, including the alcohol biomarker phosphatidylethanol 16:0/18:1 (PEth). METHODS: A cross-sectional study, lasting one year at one hospital in Oslo, Norway and one in Moscow, Russia recruiting acute medically ill patients (≥ 18 years), able to give informed consent. Self-reported data on socio-demographics, mental distress (Symptom Check List-5), alcohol use (Alcohol Use Disorder Identification Test-4 (AUDIT-4) and alcohol consumption past 24 h were collected. PEth and alcohol concentration were measured in whole blood. RESULTS: Of 5883 participating patients, 19.2% in Moscow and 21.1% in Oslo were harmful alcohol users, measured by AUDIT-4, while the prevalence of PEth-positive patients was lower: 11.4% in Oslo, 14.3% in Moscow. Men in Moscow were more likely to be harmful users by AUDIT-4 and PEth compared to men in Oslo, except of those being ≥ 71 years. Women in Oslo were more likely to be harmful users compared to those in Moscow by AUDIT-4, but not by PEth for those aged < 61 years. CONCLUSIONS: The prevalence of harmful alcohol use was high at both study sites. The prevalence of harmful alcohol use was lower when assessed by PEth compared to AUDIT-4. Thus, self-reporting was the most sensitive measure in revealing harmful alcohol use among all groups except for women in Moscow. Hence, screening and identification with objective biomarkers and self-reporting might be a method for early intervention.
BACKGROUND: The aim was to estimate the prevalence of harmful alcohol use in relation to socio-demographic characteristics among acutely ill medical patients, and examine identification measures of alcohol use, including the alcohol biomarker phosphatidylethanol 16:0/18:1 (PEth). METHODS: A cross-sectional study, lasting one year at one hospital in Oslo, Norway and one in Moscow, Russia recruiting acute medically ill patients (≥ 18 years), able to give informed consent. Self-reported data on socio-demographics, mental distress (Symptom Check List-5), alcohol use (Alcohol Use Disorder Identification Test-4 (AUDIT-4) and alcohol consumption past 24 h were collected. PEth and alcohol concentration were measured in whole blood. RESULTS: Of 5883 participating patients, 19.2% in Moscow and 21.1% in Oslo were harmful alcohol users, measured by AUDIT-4, while the prevalence of PEth-positive patients was lower: 11.4% in Oslo, 14.3% in Moscow. Men in Moscow were more likely to be harmful users by AUDIT-4 and PEth compared to men in Oslo, except of those being ≥ 71 years. Women in Oslo were more likely to be harmful users compared to those in Moscow by AUDIT-4, but not by PEth for those aged < 61 years. CONCLUSIONS: The prevalence of harmful alcohol use was high at both study sites. The prevalence of harmful alcohol use was lower when assessed by PEth compared to AUDIT-4. Thus, self-reporting was the most sensitive measure in revealing harmful alcohol use among all groups except for women in Moscow. Hence, screening and identification with objective biomarkers and self-reporting might be a method for early intervention.
Authors: Danil Gamboa; Benedicte Jørgenrud; Evgeny A Bryun; Vigdis Vindenes; Evgenya A Koshkina; Aleksei V Nadezhdin; Saranda Kabashi; Elena J Tetenova; Thomas Berg; Anna Armika Tussilago Nyman; Alexey J Kolgashkin; Aleksei E Petukhov; Sergey N Perekhodov; Elena N Davydova; Anners Lerdal; Gudmund Nordby; Stig Tore Bogstrand Journal: BMJ Open Date: 2020-09-17 Impact factor: 2.692
Authors: Hugo S Gomes; David P Farrington; Marvin D Krohn; Ana Cunha; Julia Jurdi; Bárbara Sousa; Diogo Morgado; Joseph Hoft; Elizabeth Hartsell; Leigh Kassem; Ângela Maia Journal: J Exp Criminol Date: 2022-09-21
Authors: Maria Neufeld; Jürgen Rehm; Anna Bunova; Artyom Gil; Boris Gornyi; Pol Rovira; Jakob Manthey; Elena Yurasova; Svetlana Dolgova; Bulat Idrisov; Marina Moskvicheva; Galina Nabiullina; Olga Shegaym; Irina Zhidkova; Zukhra Ziganshina; Carina Ferreira-Borges Journal: Bull World Health Organ Date: 2021-03-19 Impact factor: 9.408