Literature DB >> 31589980

Efficacy of Lenvervimab, a Recombinant Human Immunoglobulin, in Treatment of Chronic Hepatitis B Virus Infection.

Hye Won Lee1, Jun Yong Park1, Taegon Hong2, Min Soo Park3, Sang Hoon Ahn4.   

Abstract

The mechanism of action of hepatitis B immunoglobulin (HBIG) for chronic hepatitis B (CHB) treatment is not fully understood. A clinical trial in Japan suggested that HBIG therapy might benefit patients with CHB.1 Lenvervimab, a recombinant monoclonal HBIG developed by GC Pharma (Yongin, South Korea), has been screened from an anti-HBs-enriched phage-display library cloned from hepatitis B vaccine-boosted human blood cells and was produced in Chinese hamster ovary cells.2-4.
Copyright © 2020 AGA Institute. Published by Elsevier Inc. All rights reserved.

Entities:  

Year:  2019        PMID： 31589980     DOI： 10.1016/j.cgh.2019.09.038

Source DB:  PubMed          Journal:  Clin Gastroenterol Hepatol        ISSN： 1542-3565            Impact factor:   11.382


  5 in total

Review 1.  Immune Mechanisms Underlying Hepatitis B Surface Antigen Seroclearance in Chronic Hepatitis B Patients With Viral Coinfection.

Authors:  Shuling Wu; Wei Yi; Yuanjiao Gao; Wen Deng; Xiaoyue Bi; Yanjie Lin; Liu Yang; Yao Lu; Ruyu Liu; Min Chang; Ge Shen; Leiping Hu; Lu Zhang; Minghui Li; Yao Xie
Journal:  Front Immunol       Date:  2022-05-11       Impact factor: 8.786

2.  Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers.

Authors:  Verena Hehle; Maxime Beretta; Maryline Bourgine; Malika Ait-Goughoulte; Cyril Planchais; Solen Morisse; Benjamin Vesin; Valérie Lorin; Thierry Hieu; Andrea Stauffer; Oriane Fiquet; Jordan D Dimitrov; Marie-Louise Michel; Marie-Noëlle Ungeheuer; Camille Sureau; Stanislas Pol; James P Di Santo; Hélène Strick-Marchand; Nadège Pelletier; Hugo Mouquet
Journal:  J Exp Med       Date:  2020-10-05       Impact factor: 14.307

Review 3.  Viral hepatitis: Innovations and expectations.

Authors:  Simona Leoni; Alberto Casabianca; Benedetta Biagioni; Ilaria Serio
Journal:  World J Gastroenterol       Date:  2022-02-07       Impact factor: 5.742

Review 4.  A Focused Review on Recent Advances in the Diagnosis and Treatment of Viral Hepatitis.

Authors:  Wei Zhang; Mahmoud Aryan; Steve Qian; Roniel Cabrera; Xiuli Liu
Journal:  Gastroenterology Res       Date:  2021-06-19

Review 5.  Novel Biomarkers of Hepatitis B Virus and Their Use in Chronic Hepatitis B Patient Management.

Authors:  Alicia Vachon; Carla Osiowy
Journal:  Viruses       Date:  2021-05-21       Impact factor: 5.048
  5 in total

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