| Literature DB >> 31588631 |
Fei Hou1,2, Wei Wei1,2, Xiao Qin1,2, Jing Liang2,3, Sha Han2, Aizhong Han2, Qingsheng Kong2.
Abstract
Histone deacetylase 4 (HDAC4) is a member of the HDACs family, its expression is closely related to the cell development. The cell is an independent living entity that undergoes proliferation, differentiation, senescence, apoptosis, and pathology, and each process has a strict and complex regulatory system. With deepening of its research, the expression of HDAC4 is critical in the life process. This review focuses on the posttranslational modification of HDAC4 in cell biology, providing an important target for future disease treatment.Entities:
Keywords: HDAC4; cell senescence; cellular apoptosis and autophagy; glucose metabolism; inflammation and pathology; proliferation and differentiation
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Year: 2019 PMID： 31588631 DOI： 10.1002/jcb.29365
Source DB: PubMed Journal: J Cell Biochem ISSN： 0730-2312 Impact factor: 4.429