Literature DB >> 31588156

Wavelength-ratiometric and colorimetric probes for glucose determination.

Ramachandram Badugu1, Joseph R Lakowicz1, Chris D Geddes1,2.   

Abstract

We characterize two new water-soluble probes, m- and p-NBDPBA, which show notable changes in their absorption spectra in the presence of monosaccharides such as glucose and fructose. Subsequently glucose concentrations can readily be determined in the physiological glucose concentration range in a wavelength-ratiometric and colorimetric manner. m-NBDPBA has a dissociation constant of 204 mM for glucose, which is not unlike other mono-phenyl boronic acid derived probes. In addition we have also synthesized a control compound, NBDP, which does not contain the boronic acid moiety and is therefore insensitive to sugars, to help rationale the spectral changes observed.

Entities:  

Keywords:  Fructose; Glucose; Monosaccharides; Wavelength-ratiometric transduction

Year:  2005        PMID： 31588156      PMCID： PMC6777865          DOI： 10.1016/j.dyepig.2004.12.020

Source DB:  PubMed          Journal:  Dyes Pigm        ISSN： 0143-7208            Impact factor:   4.889


  8 in total

1.  Computer-Guided Design in Molecular Recognition: Design and Synthesis of a Glucopyranose Receptor This work was supported by the National Institutes of Health (grant DK5523402).

Authors:  Wei Yang; Huan He; Dale G. Drueckhammer
Journal:  Angew Chem Int Ed Engl       Date:  2001-05-04       Impact factor: 15.336

2.  New boronic acid fluorescent reporter compounds. 2. A naphthalene-based on-off sensor functional at physiological pH.

Authors:  Xingming Gao; Yanling Zhang; Binghe Wang
Journal:  Org Lett       Date:  2003-11-27       Impact factor: 6.005

Review 3.  Ophthalmic glucose monitoring using disposable contact lenses--a review.

Authors:  Ramachandram Badugu; Joseph R Lakowicz; Chris D Geddes
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

Review 4.  Fluorescent chemosensors for carbohydrates: a decade's worth of bright spies for saccharides in review.

Authors:  Haishi Cao; Michael D Heagy
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

5.  Hypoglycemia in the Diabetes Control and Complications Trial. The Diabetes Control and Complications Trial Research Group.

Authors: 
Journal:  Diabetes       Date:  1997-02       Impact factor: 9.461

6.  A new highly fluorescent probe for monosaccharides based on a donor-acceptor diphenyloxazole.

Authors:  N DiCesare; J R Lakowicz
Journal:  Chem Commun (Camb)       Date:  2001-10-07       Impact factor: 6.222

7.  The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.

Authors:  D M Nathan; S Genuth; J Lachin; P Cleary; O Crofford; M Davis; L Rand; C Siebert
Journal:  N Engl J Med       Date:  1993-09-30       Impact factor: 91.245

8.  Fluorescence sensors for monosaccharides based on the 6-methylquinolinium nucleus and boronic acid moiety: potential application to ophthalmic diagnostics.

Authors:  Ramachandram Badugu; Joseph R Lakowicz; Chris D Geddes
Journal:  Talanta       Date:  2005-02-15       Impact factor: 6.057
  8 in total

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