Literature DB >> 31586379

The effect of surgical margin positivity on survival in laryngeal cancer surgery.

Ayse Secil Kayali Dinc, Melih Cayonu, Süleyman Boynuegri, Muammer Melih Sahin, Adil Eryilmaz.   

Abstract

AIM: The aim of this retrospective study was to investigate possible factors affecting the survival in patients who were operated due to laryngeal squamous cell carcinoma (SCC) MATERIAL AND
METHOD: The study included patients who underwent surgery in our clinic due to laryngeal SCC between May 2010 and June 2018. It was learned whether the patients were alive or not by hospital records, death notification system records and patient / family interviews. Surgical reports, pathology reports, tumor clinical council notes and preoperative hematological examinations were retrospectively evaluated and recorded from the hospital registry system.
RESULTS: The mean age of the 63 patients included in the study was 59.3 (age range; 38 to 83 years). The mean postoperative follow-up period was 56.8 months (minimum 6 months to maximum 102 months). We found that surgical margin positivity had a statistically significant negative negative effect on survival (p = 0.049, r = -0.26). Perineural invasion, perivascular invasion, the presence of neck metastasis and the effect of tumor differentiation on survival were not found to be statistically significant (p values; 0.9, 0.1, 0.9 and 0.4, respectively).
CONCLUSION: The absence of a tumor at the surgical margin is one of the most basic rules in oncologic surgery. KEY WORDS: Laryngeal carcinoma, Oncologic surgery, Survival, Surgical Margin.

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Year:  2019        PMID: 31586379

Source DB:  PubMed          Journal:  Ann Ital Chir        ISSN: 0003-469X            Impact factor:   0.766


  1 in total

1.  Clinical and experimental study of a terahertz time-domain system for the determination of the pathological margins of laryngeal carcinoma.

Authors:  Jing Ke; Lifeng Jia; Yaqin Hu; Xu Jiang; Hailan Mo; Xiang An; Wei Yuan
Journal:  World J Surg Oncol       Date:  2022-10-12       Impact factor: 3.253

  1 in total

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