| Literature DB >> 31586311 |
Arun Anandakumar1, Gianluca Pellino2,3, Paris Tekkis1,4,5, Christos Kontovounisios1,4,5.
Abstract
Colorectal cancer (CRC) is the third cause of cancer-related death worldwide. It has been estimated that more than one million new cases occur every year. Several studies have investigated the role of host bacteria as agents protecting against or increasing the risk of CRC, but few have assessed the fungal microbiome in patients with CRC. Fungal dysbiosis has been studied in colorectal diseases (e.g. inflammatory bowel diseases), but few researches compared the fungal microbiome of CRC patients with those of controls. The current study represents a systematic review aimed at assessing the expression and diversity of fungi in patients with CRC and non-CRC individuals. Here, we discuss the fungal species that could be implied in CRC development and alterations that can be induced by the presence of CRC, and the potential implications for future research.Entities:
Keywords: Biomarkers; Colorectal cancer; Diagnosis; Fungal microbiome; Fungi; Treatment
Mesh：
Year: 2019 PMID： 31586311 DOI： 10.1007/s13304-019-00683-8
Source DB: PubMed Journal: Updates Surg ISSN： 2038-131X