Literature DB >> 31585103

Polyamines and Aging: A CLEAR Connection?

Douglas R Green1.   

Abstract

A decline in polyamine levels with age has been implicated in the pathophysiology of aging, and nutritional supplementation of spermidine can reduce age-related pathology and increase lifespan in a number of different organisms. In this issue of Molecular Cell, Zhang and colleagues provide a mechanistic link between polyamines, autophagy, and aging.
Copyright © 2019 Elsevier Inc. All rights reserved.

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Year:  2019        PMID: 31585103     DOI: 10.1016/j.molcel.2019.09.003

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  2 in total

1.  Exogenous spermine attenuates diabetic kidney injury in rats by inhibiting AMPK/mTOR signaling pathway.

Authors:  Xinying Zhang; Li Zhang; Zhe Chen; Siwei Li; Bingbing Che; Ningning Wang; Junting Chen; Changqing Xu; Can Wei
Journal:  Int J Mol Med       Date:  2021-02-04       Impact factor: 4.101

Review 2.  Autophagy at the intersection of aging, senescence, and cancer.

Authors:  Liam D Cassidy; Masashi Narita
Journal:  Mol Oncol       Date:  2022-07-09       Impact factor: 7.449

  2 in total

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