Literature DB >> 31584464

Escalating interventional recanalization therapy in non-cirrhotic, non-malignant acute portal vein thrombosis.

Mirjam Gerwing1, Christian Wilms2, Hauke Heinzow2, Peter B Sporns1, Walter Heindel1, Hartmut Schmidt2, Moritz Wildgruber1, Michael Köhler1.   

Abstract

OBJECTIVE: To evaluate the effectiveness of interventional therapy in acute, non-malignant, non-cirrhotic portal vein thrombosis.
METHODS: We present a retrospective study of eight consecutive patients who presented with an acute non-malignant, non-cirrhotic portal vein thrombosis and were treated by mechanical recanalization using an escalating scheme including local aspiration, thrombolysis, rheolysis and the implantation of transjugular intrahepatic portosystemic shunt or other visceral stents.
RESULTS: Recanalization rates applying the escalating scheme were good, with a success rate of 75%. However, major complications occurred in 50% of patients, mostly due to bleeding at the percutaneous access site, and minor complications in 12.5% of patients.
CONCLUSION: Interventional therapy is effective in acute portal vein thrombosis, but should only be performed at specialized centers and based on an individual treatment decision.

Entities:  

Year:  2019        PMID: 31584464     DOI: 10.1097/MEG.0000000000001559

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  3 in total

Review 1.  Portal Vein Thrombosis in Cirrhosis.

Authors:  Akash Shukla; Suprabhat Giri
Journal:  J Clin Exp Hepatol       Date:  2021-11-22

Review 2.  Consensus for management of portal vein thrombosis in liver cirrhosis (2020, Shanghai).

Authors: 
Journal:  J Dig Dis       Date:  2021-03-07       Impact factor: 2.325

3.  Interventional recanalization therapy in patients with non-cirrhotic, non-malignant portal vein thrombosis: comparison between transjugular versus transhepatic access.

Authors:  Nabeel Mansour; Osman Öcal; Mirjam Gerwing; Michael Köhler; Sinan Deniz; Hauke Heinzow; Christian Steib; Martin K Angele; Max Seidensticker; Jens Ricke; Moritz Wildgruber
Journal:  Abdom Radiol (NY)       Date:  2022-01-12
  3 in total

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