Literature DB >> 31584054

Functionalization of activated methylene C-H bonds with nitroarenes and sulfur for the synthesis of thioamides.

Nhan T Do1, Khoa M Tran1, Hao T Phan1, Tuong A To1, Tung T Nguyen1, Nam T S Phan1.   

Abstract

We report a method to obtain arylthioamides by the functionalization of sp3 C-H bonds in phenylacetic acids and benzyl alcohols. Reactions proceeded without the use of any solvents and were compatible with many functionalities and heterocycles. These conditions allow for a rapid synthesis of thioamides from simple, commercial substrates.

Entities:  

Year:  2019        PMID： 31584054     DOI： 10.1039/c9ob01751h

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  2 in total

1.  Synthesis of primary N-arylthioglyoxamides from anilines, elemental sulfur and primary C-H bonds in acetophenones.

Authors:  Khoa M Tran; Nguyen H K Nguyen; Thuy T Bui; Tuong A To; Nam T S Phan; Ha V Le; Tung T Nguyen
Journal:  RSC Adv       Date:  2020-12-18       Impact factor: 4.036

2.  New synthesis of 2-aroylbenzothiazoles via metal-free domino transformations of anilines, acetophenones, and elemental sulfur.

Authors:  Tien V Huynh; Khang V Doan; Ngoc T K Luong; Duyen T P Nguyen; Son H Doan; Tung T Nguyen; Nam T S Phan
Journal:  RSC Adv       Date:  2020-05-14       Impact factor: 3.361
  2 in total

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